Collection of Cell Aging—The Road Map of Aging

Dear Colleagues,

Aging is accompanied by a continuous decline in the capacity to maintain organ homeostasis and function. At the same time, the median human lifespan continues to increase. Thus, understanding the molecular and cellular mechanisms that underlie the aging process is of significant societal impact and high scientific interest. In recent years, exciting progress has been made regarding several aspects of research on aging, such as senescence, stem cell biology, sex-specific aspects of aging, and epigenetics. Moreover, the reprogramming phenomenon and the development of senolytics have contributed to the vision that a deceleration of at least some aspects of aging might be in sight. 

With this topic collection, we want to cover a wide array of topics, including but not limited to aging-associated changes in the epigenome, the cellular surveillance of protein homeostasis, damage response, cellular senescence, stem cell function and tissue regeneration, the aging of the immune system, the links between metabolism and aging, aging clocks, and aging-associated diseases. We also invite the submission of manuscripts on the translational aspects of research on aging, including those on the development of interventions in model organisms and humans.

Prof. Dr. Christoph Englert
Collection Editor

Manuscript Submission Information

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