Application of Neurophysiological Studies in the Treatment of Epilepsy

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurotechnology and Neuroimaging".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 4

Special Issue Editors


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Guest Editor
Clinical Neurophysiology, Hospital Universitario de la Princesa, Madrid, Spain
Interests: epilepsy; quantified EEG; multivariate numerical analysis; deep brain stimulation; intraoperative neurophysiological monitoring; EEG monitoring
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Clinical Neurophysiology; Hospital Universitario de la Princesa, Madrid, Spain
Interests: epilepsy; quantified EEG; multivariate numerical analysis; deep brain stimulation; intraoperative neurophysiological monitoring; EEG monitoring
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Electroencephalography (EEG) is the measurement of brain currents and, although not exclusively, it is especially used in the diagnosis and clinical management of epilepsy. Even though other complementary techniques, such as imaging techniques, are very useful, the pathophysiology of epilepsy, as a primary alteration of neuronal excitability, means that neurophysiological methods remain essential. In recent years, we have witnessed the emergence and the slow but steady rise in use in clinical practice of new tools, such as quantified EEG (qEEG) or electrical source imaging techniques, which are adding a new perspective to conventional ones such as resting-state EEG, electrocorticography, or video-EEG. These new tools promise to improve the clinical management of epileptic patients, both in the diagnosis and therapeutic adjustment of both kinds of patients, those with drug-sensitive epilepsy, and in the preoperative assessment of patients with drug-resistant epilepsy. Related bioelectrical measurement techniques, such as chronic intracerebral recording and the possibility of pharmacological or electrical treatment during the onset of seizures, will see considerable development in the coming years. New devices for seizure forecasting are attracting considerable interest.

In this Special Issue, we aim to collect original research and review articles focusing on novel diagnostic and therapeutic methods based on the measurement of bioelectric activity in epileptic patients.

Dr. Jesús Pastor
Dr. Lorena Vega-Zelaya
Guest Editors

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Keywords

  • brain source localization
  • electrocorticography
  • electromagnetic tomography
  • intracranial EEG
  • quantified EEG
  • seizure forecasting

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