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Biosensors
Special Issues
Advances in Wearable Sweat Biosensing Technologies
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Advances in Wearable Sweat Biosensing Technologies

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Wearable Biosensors".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 5886

Special Issue Editor

Dr. Lie Wang

E-Mail Website
Guest Editor
College of Engineering and Applied Sciences, Nanjing University, Nanjing 210023, China
Interests: fiber electronics; wearable devices; bioelectronics; electrochemical sensors

Special Issue Information

Dear Colleagues,

Wearable sweat-sensing technologies have received wide attention for personalized health monitoring with continuous and molecular-level insight in a noninvasive manner. Substantial progress has been made in developing wearable sweat biosensors into various formats, such as patches, tattoos, and fabrics for detecting different biomarkers, e.g., glucose, lactate, electrolytes, and pH. They possess many appealing characteristics, e.g., lightweight, flexibility, stretchability, and conformability, which are important for wearable applications. In this Special Issue, we would like to invite you to contribute research articles, reviews, or perspectives related to “Advances in Wearable Sweat Biosensing Technologies”. The welcomed topics include, but are not limited to, biosensing material synthesis, biosensor fabrication, sweat extraction, health monitoring, disease detection, and sweat-sensing technology development.

Kind regards,

Dr. Lie Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • wearable devices
  • electrochemical sensors
  • noninvasive biosensors
  • sweat
  • real-time health monitoring

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

12 pages, 5494 KiB  
Communication
Laser-Cutted Epidermal Microfluidic Patch with Capillary Bursting Valves for Chronological Capture, Storage, and Colorimetric Sensing of Sweat
by Yuxin He, Lei Wei, Wenjie Xu, Huaping Wu and Aiping Liu
Biosensors 2023, 13(3), 372; https://doi.org/10.3390/bios13030372 - 12 Mar 2023
Cited by 8 | Viewed by 2914
Abstract
Flexible wearable microfluidic devices show great feasibility and potential development in the collection and analysis of sweat due to their convenience and non-invasive characteristics in health-level feedback and disease prediction. However, the traditional production process of microfluidic patches relies on resource-intensive laboratory and [...] Read more.
Flexible wearable microfluidic devices show great feasibility and potential development in the collection and analysis of sweat due to their convenience and non-invasive characteristics in health-level feedback and disease prediction. However, the traditional production process of microfluidic patches relies on resource-intensive laboratory and high-cost facilities. In this paper, a low-cost laser-cutting technology is proposed to fabricate epidermal microfluidic patches for the collection, storage and colorimetric analysis of sweat. Two different types of capillary bursting valves are designed and integrated into microchannel layers to produce two-stage bursting pressure for the reliable routing of sweat into microreservoirs in sequential fashion, avoiding the mixing of old and new sweat. Additionally, an enzyme-based reagent is embedded into the microreservoirs to quantify the glucose level in sweat by using colorimetric methods, demonstrating a high detection sensitivity at the glucose concentration from 0.1 mM to 1 mM in sweat and an excellent anti-interference performance that prevents interference from substances probably existent in sweat. In vitro and on-body experiments demonstrate the validity of the low-cost, laser-cut epidermal microfluidic patch for the chronological analysis of sweat glucose concentration and its potential application in the monitoring of human physiological information. Full article
(This article belongs to the Special Issue Advances in Wearable Sweat Biosensing Technologies)
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14 pages, 7133 KiB  
Article
Full-Cut Manufacture of Skin-Interfaced Microfluidic Patch with Copper Electrode for In Situ Admittance Sensing of Sweat Rate
by Lei Wei, Yuxin He, Zihan Lv, Daoyou Guo, Lin Cheng, Huaping Wu and Aiping Liu
Biosensors 2023, 13(1), 67; https://doi.org/10.3390/bios13010067 - 31 Dec 2022
Cited by 4 | Viewed by 2605
Abstract
Sweat-rate measurement has received more and more attention, especially for specific groups, such as athletes, soldiers and manual workers, due to their excessive sweat loss under prolonged intense heat stress, which increases the risk of dehydration and electrolyte imbalance. The highly effective manufacture [...] Read more.
Sweat-rate measurement has received more and more attention, especially for specific groups, such as athletes, soldiers and manual workers, due to their excessive sweat loss under prolonged intense heat stress, which increases the risk of dehydration and electrolyte imbalance. The highly effective manufacture of a sweat-sensing device is essential to its wide range of applications in perspiration-related physiological information detection. In this work, we propose a simple and cost-effective strategy for the manufacture of a microfluidic sweat-rate-sensing patch via laser cutting and transfer printing technology. A copper foil tape is used as the electrode for in situ admittance based sweat-rate-sensing. The detection circuits and measurement conditions are optimized to prevent the negative effect of an electrochemical reaction between a copper electrode and sweat for precise admittance measurement. In vitro and on-body experiments demonstrate that the copper electrode is applicable for admittance-based sweat sensing and is capable of achieving equivalent sensing accuracy as a gold electrode and that the proposed sensor structure can perform consecutive and accurate sweat-rate-sensing and facilitates a significant increase in manufacturing efficiency. Full article
(This article belongs to the Special Issue Advances in Wearable Sweat Biosensing Technologies)
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