Special Issue "Advances in Biosensors Based on Reflectometry"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".

Deadline for manuscript submissions: 31 August 2023 | Viewed by 105

Special Issue Editors

Institute of Physical and Theoretical Chemistry, Eberhard Karls Universität, Auf der Morgenstelle 18, 72076 Tübingen, Germany
Interests: optical biosensors; label-free high-throughput screening of biopharmaceuticals; process monitoring; immunoassays; biomolecular interactions; assay development for point-of-care testing (POCT) and environmental sensing; environmental analysis; effect directed analytics; bioanalytics; microarrays; infectious diseases; immunology; surface chemistry; microfluidics
Institute of Physical and Theoretical Chemistry, Eberhard Karls Universität, Auf der Morgenstelle 18, 72076 Tübingen, Germany
Interests: biochemistry; biosensors; kinetics; effect directed analytics; molecular diagnostics; AI; optics; label-free screening

Special Issue Information

Dear Colleagues,

Today, direct optical biosensors have found their place in bioanalytics since they provide valuable data on kinetics and thermodynamics, do not require complicated sample pre-treatment and can be used for direct test formats. In the last 10-15 years, reflectometric measurement methods in particular, which are usually derived from ellipsometry, have gained in importance over refractometric transduction principles, although the boundaries between these areas sometimes seem to become blurred. Basically, however, reflectometry in biosensing is characterized by the typical feature that multiple reflections of electromagnetic radiation on at least one thin layer are used for signal generation. The driving force behind the many current developments is, among other things, applications that benefit, for example, from the ease of parallelization, the connection to common sample handling formats or, finally, the robustness towards temperature fluctuations in real-world operation. Against this background, this special issue of "Biosensors" will highlight the latest developments in reflectometric transduction and report on current applications such as the screening of biologics, biomolecular interaction analysis of receptors and ligands relevant to molecular medicine, as well as cell-based assays and diagnostics. All components of the biosensor, from the sensor surface to microfluidics and data analysis, are relevant, regardless in which area this technology is used.

Dr. Günther Proll
Dr. Peter Fechner
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • biosensor
  • reflectometry
  • label-free
  • kinetics
  • biomolecular interaction analysis
  • optical transduction
  • screening
  • biologics
  • cell-based assays

Published Papers

This special issue is now open for submission.
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