Research Progress and Future Trends of Microfluidic Analytical Devices

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Nano- and Micro-Technologies in Biosensors".

Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 2043

Special Issue Editors


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Guest Editor
Department of Chemical and Materials Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA
Interests: biosensor; electrochemical; micro-nanofluidics; electro-kinetics
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Guest Editor
Visiting Research Scientist, New Jersey Institute of Technology, Newark, NJ, USA
Interests: microfluidics; electrochemical sensors; point-of-use devices; PFAS screening
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Miniaturization of analytical instruments such as electrophoresis, UV-VIS spectroscopy, and mass spectrometry is driven by a need to reduce cost by consumption of low volumes of expensive fluids and reagents, achieve multiplexing, and increase throughput by automation. A recent research trend is fabricating small and smaller electronic, mechanical, and optical devices to provide a faster, real-time response and more selective and sensitive detection. Among the many developed techniques, microfluidics has been a choice of technique to fabricate devices due to the advantages of controllability, reproducibility, stability with small volumes, and reaction for testing. Microfluidics-based analytical sensors have been widely used in various applications such as point-of-care diagnostics, environmental monitoring, pathogen detection in food, healthcare monitoring, water quality, drug testing, and various chemical and biological domains.

For this Special Issue, we invite original research articles, communications, and review papers focusing on cutting-edge research and innovation in fabricating microfluidics-based analytical devices, including biosensors, paper-based analytical devices, electrochemical sensors, and optical sensors for the point-of-care diagnosis, environmental monitoring, detection of diseases such as COVID-19, detection of emerging contaminants and much more. This Special Issue will focus on applications including, but not limited to, food safety, water quality, forensic, plant-based pathogens, environmental monitoring, healthcare, and drug development. 

Dr. Sagnik Basuray
Dr. Charmi Chande
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • paper-based analytical devices
  • biosensors
  • microfluidics-based sensors
  • mass spectroscopy
  • point-of-care diagnostics
  • electrochemical sensors
  • optical sensors
  • emerging diseases
  • emerging contaminants

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Published Papers (1 paper)

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Research

17 pages, 4204 KiB  
Article
Bidirectional and Stepwise Rotation of Cells and Particles Using Induced Charge Electroosmosis Vortexes
by Shaoxi Wang, Zhexin Zhang, Xun Ma, Yuanbo Yue, Kemu Li, Yingqi Meng and Yupan Wu
Biosensors 2024, 14(3), 112; https://doi.org/10.3390/bios14030112 - 20 Feb 2024
Viewed by 1505
Abstract
The rotation of cells is of significant importance in various applications including bioimaging, biophysical analysis and microsurgery. Current methods usually require complicated fabrication processes. Herein, we proposed an induced charged electroosmosis (ICEO) based on a chip manipulation method for rotating cells. Under an [...] Read more.
The rotation of cells is of significant importance in various applications including bioimaging, biophysical analysis and microsurgery. Current methods usually require complicated fabrication processes. Herein, we proposed an induced charged electroosmosis (ICEO) based on a chip manipulation method for rotating cells. Under an AC electric field, symmetric ICEO flow microvortexes formed above the electrode surface can be used to trap and rotate cells. We have discussed the impact of ICEO and dielectrophoresis (DEP) under the experimental conditions. The capabilities of our method have been tested by investigating the precise rotation of yeast cells and K562 cells in a controllable manner. By adjusting the position of cells, the rotation direction can be changed based on the asymmetric ICEO microvortexes via applying a gate voltage to the gate electrode. Additionally, by applying a pulsed signal instead of a continuous signal, we can also precisely and flexibly rotate cells in a stepwise way. Our ICEO-based rotational manipulation method is an easy to use, biocompatible and low-cost technique, allowing rotation regardless of optical, magnetic or acoustic properties of the sample. Full article
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