Special Issue "Insights into the Oral Microbiome and Its Modulation"

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 30 September 2023 | Viewed by 93

Special Issue Editors

School of Dentistry, Faculty of Medicine and Health, University of Leeds, Leeds, UK
Interests: NGS; oral microbiome; biofilms; dysbiosis; health; systemic diseases; bioinformatics; metagenomics; metatranscriptomics
Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands
Interests: oral microbiome; biofilms; host-microbe interaction
Special Issues, Collections and Topics in MDPI journals
1. Department of Dentistry, University of Brasília, Brasilia, Brazil
2. The Division of Oral Biology, University of Leeds, Leeds, UK
Interests: dental caries; oral microbiome; saliva; biofilms; low-abundance microbiota; oral archaeome

Special Issue Information

Dear Colleagues,

The human oral cavity harbours more than 700 microbial species. These microbes form a complex and diverse microbial community and inhabit different niches in the oral cavity. In a healthy state, the oral microbiome and the host tissue maintain a delicate balance and form a symbiotic relationship. However, environmental stresses, for example, poor oral hygiene or systemic inflammatory disease can shift the composition of the oral microbiome from homeostasis to dysbiosis and eventually contribute to the development of oral diseases such as dental caries, periodontitis, and candidiasis. To prevent and treat these diseases, we used to focus on microbe removal/death. With the improved knowledge of the oral ecosystem, microbiome modulation strategies are being implemented that aim to restore the homeostasis between the microbiome and the host.

This Special Issue will focus on the current state-of-the-art methods and knowledge of oral disease treatment and prevention.

We welcome original papers and reviews (including systematic and scoping reviews) that investigate and discuss at least one of the following:

  • Association of the oral microbiome and systemic diseases.
  • Microbiome modulation strategies or other novel strategies to treat and/or prevent oral dysbiosis.
  • The use of the oral microbiome as a biomarker for the early diagnosis of oral and systemic diseases.
  • Complex interactions that are at play, including environmental factors (the importance of clinical and metadata in NGS analyses).

Dr. Thuy Do
Dr. Dongmei Deng
Dr. Nailê Damé-Teixeira
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2300 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • oral microbiome
  • oral infectious diseases
  • systemic disease

Published Papers

This special issue is now open for submission.
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