Endothelial Health in Atherosclerosis: From Function to Dysfunction and Beyond

Dear Colleagues,

The endothelium plays a crucial role in maintaining vascular homeostasis, regulating blood flow, and preventing atherosclerosis. However, endothelial dysfunction, characterized by impaired nitric oxide bioavailability, oxidative stress, and chronic inflammation, is a key driver of atherogenesis. Understanding the molecular mechanisms underlying endothelial function and dysfunction is essential for developing targeted therapies to prevent and treat cardiovascular diseases.

This Special Issue aims to explore the dynamic role of endothelial cells in atherosclerosis, covering topics from endothelial protection to pathological dysfunction. We welcome studies that investigate molecular mechanisms, biomarkers, novel therapeutic targets, and interventions to restore endothelial health. This aligns with Biomolecules’ focus on molecular and cellular mechanisms of disease, offering a platform for cutting-edge research in cardiovascular biology.

We invite original research articles, reviews, and short communications on topics including:

• Molecular pathways of endothelial dysfunction in atherosclerosis
• Role of oxidative stress and inflammation in endothelial health
• Biomarkers and diagnostic tools for endothelial dysfunction
• Therapeutic strategies targeting endothelial repair
• The impact of lifestyle and pharmacological interventions on endothelial function

Dr. Yuqi Cui
Dr. Zhenguo Liu
Guest Editors

Manuscript Submission Information

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