Advances in Various Roles of High-Density Lipoproteins
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Lipids".
Deadline for manuscript submissions: 15 February 2026 | Viewed by 13
Special Issue Editor
2. Faculty of Sports and Health Science, Fukuoka University, 8-19-1 Nanakuma, Johnan-ku, Fukuoka 814-0180, Japan
Interests: atherosclerosis; HDL; lipid metabolism; sports medicine; function of skeletal muscle
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In modern society, atherosclerotic diseases, in addition to cancer, are a significant group of conditions affecting lifespan. Although medications that lower low-density lipoprotein (LDL) cholesterol are widely used in clinical practice, drugs that increase high-density lipoprotein (HDL) cholesterol have yet to be used clinically. Consequently, HDL's role in promoting health and extending lifespan is not clearly understood, and the complexity of HDL metabolism and its numerous associated factors may hinder our understanding of the importance of HDL cholesterol.
In this Special Issue, we explore the various pleiotropic functions of HDL in diseases such as atherosclerosis and metabolic conditions, discussing their potential therapeutic applications. We highlight recent advances in understanding the various roles of high-density lipoproteins, including research into their function and structure. Additionally, we examine the potential of HDL-based therapies to mitigate cardiovascular risk and improve metabolic health. By synthesizing current knowledge and future directions, this Special Issue aims to deepen our understanding of HDL’s multifaceted contributions to disease prevention and longevity.
Prof. Dr. Yoshinari Uehara
Guest Editor
Manuscript Submission Information
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Keywords
- atherosclerosis
- high-density lipoprotein (HDL)
- HDL functions
- apolipoproteins
- lipid and glucose metabolism
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