Molecular Genetics and Cell Biology in Neuroblastoma
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Cellular Biochemistry".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 5
Special Issue Editor
2. Department of Development, Glycostem Therapeutics BV, 5349 AB Oss, The Netherlands
Interests: bio-informatics; cancer research; cell therapy; gene therapy
Special Issue Information
Dear Colleagues,
Neuroblastoma (NB) is a pediatric tumor arising from the sympathetic nervous system. It is the most common cancer in infants and the third-most common cancer in children after leukemia and glioblastoma, accounting for 7% of cancers in childhood. NB is extremely heterogeneous, and it can spontaneously regress or rapidly metastasize and become therapy-resistant. In spite of intensive multimodal therapy, the rate of successful treatment of aggressive NB is still only 50%, with severe long-term consequences for patients who survive. NB still causes 15% of cancer-related deaths in children.
There is a clear need for new NB therapy strategies. With the recent developments in high-throughput and single-cell sequencing and molecular profiling and advances in bio-informatics, the time has come for us to fully elucidate NB’s complex etiology and identify novel and game-changing therapy targets.
For this Special Issue, we invite manuscripts exploring NB etiology, NB classification, and novel NB therapies.
Dr. Dirk Geerts
Guest Editor
Manuscript Submission Information
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Keywords
- genetics
- genomics
- neuroblastoma
- precision medicine
- transcriptomics
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