Immunometabolism and Signaling Networks in Autoimmune Rheumatic Diseases
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 20 July 2026 | Viewed by 31
Special Issue Editors
Interests: vasculitis; rheumatoid arthritis; giant cell arteritis; Takayasu arteritis; ANCA-associated vasculitis
Interests: systemic lupus erythematosus; Sjögren's disease; rheumatoid arthritis; familial mediterranean fever
Special Issue Information
Dear Colleagues,
Autoimmune rheumatic diseases arise from persistent immune activation, accompanied by profound alterations in cellular metabolism and intracellular signaling. Recent advances have revealed that metabolic pathways not only support immune function but also actively shape immune cell differentiation, survival, and pathogenicity through tightly regulated signaling networks. Dysregulated metabolicsignaling coupling in lymphocytes, myeloid cells, and stromal tissues contributes to chronic inflammation, tissue damage, and therapeutic resistance. This Special Issue aims to provide an integrative platform for original research and critical reviews that explore the molecular mechanisms linking immunometabolism and signaling pathways, focusing on disease pathogenesis, biomarkers, and innovative therapeutic strategies for autoimmune rheumatic disorders.
Dr. Ryu Watanabe
Dr. Yushiro Endo
Guest Editors
Manuscript Submission Information
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Keywords
- immunometabolism
- intracellular signaling pathways
- T-cell and B-cell metabolism
- metabolic–signaling crosstalk
- innate immune cell signaling
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