Addiction: Molecular Research and Novel Therapeutic Approaches

Dear Colleagues,

Addiction is a widespread, disabling condition, among the first causes of global burden of disease. Few pharmacological choices and non-pharmacological approaches (e.g., neuromodulation techniques) are currently available to deal with this condition. However, these approaches are not satisfactory. Additional treatments are needed, and in order to proceed further, a clearer understanding of biological processes that underlie addiction is needed.

Molecular mechanisms play a vital role in this understanding (https://www.mdpi.com/journal/ijms/special_issues/Insights_Psychiatry, https://www.mdpi.com/journal/ijms/special_issues/Endocannabinoids_2). We need to integrate altered molecular pathways with disease expression, behavior, and neuronal circuitry, and to form a complete theory with significant clinical implications, both for diagnosis and treatment.

This Special Issue is dedicated to molecular research in the field of addiction. Both substance use disorders and novel behavioral addictions are to be considered the subject of the Issue. Manuscripts about biomarkers, genetics, pathophysiological mechanisms that underlie the disorder, and translational research are particularly welcome. On the side of treatments, manuscripts regarding pharmacological approaches are of particular interest for this Special Issue. Manuscripts dealing with non-pharmacological approaches with a strong biological rationale (e.g., neuromodulation techniques) are also welcome.

Dr. Francesco Di Carlo
Dr. Giovanni Martinotti
Prof. Dr. Magí Farré
Guest Editors

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