Innovative Approaches in In Vitro Models: From Design to Application

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Biomedical Engineering and Materials".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 6

Special Issue Editor

1. The Institute of Biomedical Sciences, Faculty of Medicine, University of Maribor, Taborska ulica 8, 2000 Maribor, Slovenia
2. The Department of Pharmacology, Faculty of Medicine, University of Maribor, Taborska ulica 8, 2000 Maribor, Slovenia
Interests: polysaccharide-based hydrogels; 3D bioprinting and skin-on-a-chip models; wound dressings; controlled drug delivery; regenerative and in vitro tissue models
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Special Issue Information

Dear Colleagues,

This Special Issue, titled “Innovative Approaches in In Vitro Models: From Design to Application”, will focus on the development and application of advanced in vitro systems that more accurately mimic human physiology and pathology. These models are essential for understanding disease mechanisms, drug responses, and regenerative processes, while reducing reliance on animal testing. This issue welcomes contributions covering novel cell isolation and characterization techniques that enable the use of primary human cells and patient-derived tissues for personalized model design. Emphasis will be placed on innovative model platforms such as 3D-bioprinted tissues, organ-on-a-chip systems, microfluidic devices, and multi-layer constructs that reproduce key aspects of human organs and diseases, including vascularization, inflammation, fibrosis, and wound healing. Technological advances in biosensing, imaging, and microfabrication, which support dynamic and functional readouts, are also of great interest. By bridging cell biology, bioengineering, and translational medicine, this Special Issue aims to highlight integrative approaches that enhance the physiological relevance, predictive power, and clinical applicability of next-generation in vitro models for studying human disease.

Dr. Tina Maver
Guest Editor

Manuscript Submission Information

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Keywords

  • in vitro disease models
  • human cell isolation and characterization
  • organ-on-a-chip and microfluidic systems
  • 3D bioprinting and tissue engineering
  • translational biomedical research

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Published Papers

This special issue is now open for submission.
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