Autoimmune and Inflammatory Disorders: From Pathogenesis to Therapeutic Targeting
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 27
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue, “Autoimmune and Inflammatory Disorders: From Pathogenesis to Therapeutic Targeting,” aims to highlight recent advances in understanding immune dysregulation and its therapeutic implications. We welcome original research and reviews focusing on the molecular mechanisms underlying autoimmune and chronic inflammatory diseases, particularly the role of inflammasomes in regulating innate immune responses. Submissions exploring how inflammasome activation contributes to the pathogenesis of sepsis, chronic inflammation, and autoimmune disorders are of particular interest. We also encourage studies proposing strategies to modulate inflammasome activity, such as small-molecule inhibitors, genetic approaches, or upstream signaling modulators, to restore immune balance and ameliorate disease progression. In addition, we invite contributions that investigate the microbiota–immune axis, including how microbial communities, metabolites, or microbe–host interactions regulate immune responses and impact disease development or resolution. Research that links microbiota composition or function with inflammasome regulation or immune tolerance mechanisms will be especially relevant. Overall, this Special Issue seeks to bridge basic mechanistic insights with translational potential, providing a platform for discoveries that advance our understanding of immune-mediated diseases and support the development of novel therapeutic interventions targeting inflammatory and autoimmune pathways.
Dr. Yu-Wei Chang
Guest Editor
Manuscript Submission Information
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Keywords
- inflammasome
- inflammation
- sepsis
- autoimmune
- microbiota
- immunomodulation
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