Cutting-Edge Biomechanics: Unlocking the Future of Biomedical Engineering

Dear Colleagues,

We are pleased to invite high-impact contributions to our forthcoming Special Issue, “Cutting-Edge Biomechanics: Unlocking the Future of Biomedical Engineering”. This Special Issue will highlight the most advanced and transformative developments at the interface of biomechanics and biomedical engineering—an interdisciplinary nexus that is rapidly reshaping our understanding of biological systems and catalyzing innovation in healthcare technologies.

As global health challenges continue to evolve, the demand for novel diagnostic tools and therapeutic strategies becomes increasingly urgent. Biomechanics—through the integration of engineering principles with biological, medical, and computational sciences—offers powerful insights into the physical basis of health and disease. Emerging breakthroughs in computational modeling, experimental techniques, and high-resolution imaging are driving a new era of biomechanical discovery, unlocking the mechanistic underpinnings of physiological function and pathology.

This Special Issue will showcase pioneering research that not only deepens fundamental knowledge but also accelerates translation from bench to bedside. From predictive models of organ mechanics to patient-specific device design, the contributions in this Special Issue aim to inform clinical decision making, enhance therapeutic efficacy, and ultimately improve patient outcomes.

We seek to foster an authoritative forum for state-of-the-art research and thought-provoking perspectives that challenge conventional paradigms, stimulate novel research directions, and shape the future of biomedical innovation.

We welcome original research articles, reviews, and perspectives across a broad range of topics, including but not limited to the following:

• Computational Biomechanics and Modeling: Finite element analysis, multiscale and patient-specific modeling.
• Experimental Biomechanics: Innovative in vitro/in vivo methods, dynamic mechanical testing, imaging-based characterization.
• Cellular and Molecular Biomechanics: Mechanotransduction, cell–matrix mechanics, mechanobiology of disease.
• Tissue Biomechanics and Regenerative Engineering: Tissue remodeling, mechanobiology of development and repair, bioinspired scaffold design.
• Cardiovascular Biomechanics: Hemodynamics, arterial wall mechanics, heart valve function, device–tissue interactions.
• Musculoskeletal Biomechanics: Joint mechanics, bone adaptation, orthopedic implants, neuromuscular rehabilitation.
• Sports and Injury Biomechanics: Impact analysis, injury risk prediction, performance optimization.
• Biomaterials and Medical Device Innovation: Mechanical evaluation of biomaterials, prosthetic design, functional testing.
• Medical Robotics and Haptics: Surgical simulation, sensor-integrated rehabilitation devices, human–machine interfaces.
• AI and Machine Learning in Biomechanics: Data-driven modeling, real-time analytics, image processing and classification.

We look forward to your contributions and to curating a collection that will serve as a definitive reference for the next generation of biomechanics research and biomedical engineering advancement.

Dr. Ye Zeng
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomechanics is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• computational biomechanics
• experimental biomechanics
• cellular and molecular biomechanics
• tissue biomechanics and regenerative engineering
• cardiovascular biomechanics
• musculoskeletal biomechanics
• sports and injury biomechanics
• biomaterials and medical device innovation
• medical robotics and haptics
• AI and machine learning in biomechanics