Study on the Relationship between Microglial Activity and Neurogenesis
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Neuroscience".
Deadline for manuscript submissions: closed (30 June 2021) | Viewed by 199
Special Issue Editor
Interests: neuroembryology; congenital anomaly; neuro-inflammation; neurogenesis; cell proliferation; microglia; neurodevelopmental toxicology; neurodevelopment
Special Issue Information
Dear Colleagues,
It has been suggested that microglia significantly change their functions and characteristics during the prenatal period and after maturity of an individual. During the developmental period, microglia are involved in brain morphogenesis. It has also been suggested that neuroinflammation and abnormal activation of microglia are one of the causes of abnormal brain morphogenesis caused by exposure to chemical substances during the prenatal period. We aim to clarify the correlation between developmental toxicity and congenital anomalies in brain morphogenesis and microglial abnormalities.
Are microglial abnormalities and neuroinflammation common phenomena in chemical exposure, stress, and infections that cause birth defects in the brain? Exposure to certain chemicals, such as ethanol, has been reported to cause abnormal activation of microglia and neuroinflammation. It can be clarified whether abnormalities in microglia can occur as one of the causes of neurogenic toxicity.
This Special Issue welcomes the submission of original research and review manuscripts focusing on the role of microglia in morphogenesis of the brain, and we hope it can clarify the relationship between microglial abnormalities and congenital anomalies and brain morphogenesis.
Dr. Munekazu Komada
Guest Editor
Manuscript Submission Information
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Keywords
- neurogenesis
- neuroinflammation
- brain morphogenesis
- microglia
- neurodevelopmental toxicology
- prenatal and postnatal exposure
