Modelling Monogenic Human Diseases

Dear Colleagues,

In the recent years, increasing numbers of models have been developed to study the different aspects of human genetic disease. With the nowadays easy access to genome editing tools, animal and cell lines reproducing human disease are being developed. Such models are amazing platforms for the evaluation of new therapeutic approaches and/or large-scale drug screening.

In this Special Issue entitled “Modeling Monogenic Human Diseases”, we invite the submission of original scientific reports, review articles, commentaries, and perspective pieces on the broad topic of models of human diseases. We wish to cover a wide panel of pathologies affecting different organs, using in vitro and in vivo approaches. The focus will be put on (1) research articles about the development of these new models and their use in translational approaches and (2) reviews about the comparison between existing disease models with their strengths and limitations.

This Special Issue will be a comprehensive collection of articles and an incredible resource for scientists within the field of translational research and for biological science in general.

Dr. Antony Cougnoux
Guest Editor

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