Animal Models of Retinal Degenerative Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Neuroscience".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 47
Special Issue Editors
Interests: neuroscience; retinal degeneration; ocular diseases; genome editing; mouse model
2. Research Service, Tibor Rubin VA Long Beach Medical Center, Long Beach, CA 90822, USA
3. Center for Translational Vision Research, Gavin Herbert Eye Institute, Department of Ophthalmology, University of California Irvine, Irvine, CA 92697, USA
Interests: animal models; retinal degeneration; retinal biochemistry; ocular gene therapy
Special Issue Information
Dear Colleagues,
This Special Issue focuses on "Animal Models of Retinal Degenerative Diseases," providing a comprehensive exploration of the indispensable role of vision. Vision not only enriches the human experience by facilitating social interactions, literacy, and cognitive development but also remains critically vulnerable to various degenerative conditions. Retinal degenerative diseases significantly impair this crucial sense, leading to considerable challenges in daily life. To advance our understanding of these diseases, animal models, particularly those that incorporate human mutations or are humanized at the genetic level, are invaluable. These models offer insights into the disease mechanisms at play and are fundamental in the progression from pathological understanding to therapeutic innovation. Through detailed characterizations of genotype–phenotype correlations, these models illuminate the intricate biology of retinal diseases. This Special Issue aims to introduce the latest research on animal models of retinal degenerative diseases. It will cover a range of topics, including the detailed characterization of these models, the relationship between genetic mutation and disease manifestation, and the development and assessment of novel treatments.
Dr. Elliot H. Choi
Dr. Marco Bassetto
Guest Editors
Manuscript Submission Information
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Keywords
- retinal degeneration
- inherited retinal diseases
- retina
- retinal pigment epithelium
- animal models
- photoreceptors
- retinal ganglion cells
- choroid
- neovascularization
