Special Issue "Inflammation-Associated Cancers: From Molecular Targets to Therapeutics"

A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: 30 June 2020.

Special Issue Editor

Dr. Pasqualina Liana Scognamiglio

Guest Editor
Affiliation Center for Advanced Biomaterials for Health Care, Italian Institute of Technology, @ CRIB Largo Barsanti e Matteucci, 53 80125 - Naples, Italy

Special Issue Information

Dear Colleagues,

Inflammation is a physiological mechanism that, if unregulated, can became chronic, inducing malignant growth and tumorigenesis due to the persistent production of several inflammatory mediators. Oxidants, cytokines, chemokines, matrix metalloproteinases, and transcription factor populate the tumor microenvironment, acting directly on cancer cells, inhibiting their apoptosis, encouraging their proliferation, and leading to oncogenic mutations. Recently, therapeutic strategies to limit inflammatory cells and their mediators have been successful in pre-clinical and clinical tumor models. The Food and Drug Administration (FDA) approval of two recombinant cytokines, IL-2 and INF-α, for the treatment of numerous malignant diseases was the first demonstration that this kind of therapy could favor the balance between cancer and the anti-tumor immune response. These hopeful results open the route for new treatments able to reduce cancer-promoting inflammation and enhance anti-tumor efficacy.

In this Special Issue, contributions are encouraged to discuss pathogenesis and novel screening strategies, molecular targets, and therapeutics for inflammatory-associated cancer diseases. It is envisioned that this Special Issue will help readers to become more familiar with advances on discovery and development of effective treatments for inflammation-associated cancers.

Dr. Pasqualina Scognamiglio
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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