Special Issue "Heat Shock Proteins Associated with Immune Response"
A special issue of Biology (ISSN 2079-7737).
Deadline for manuscript submissions: 31 December 2020.
Interests: vaccines; autoimmunity; T cells; immunotherapy; HSP; arthritis
Interests: dendritic cells; tolDC; mucosal tolerance; vaccines; Treg; translational immunology
Interests: immunoregulation; T cell receptors; T cell assays; Tregs
Heat shock proteins (HSP) have attracted ample attention from immunologists over the last few years. The earliest discoveries on HSPs were made concerning their dominant role in humoral immune responses following bacterial infection. Since then, HSP have been found to also have direct interactions with receptors of the innate immune system, including those associated with dendritic cells. Antibodies and also T cell responses with specificity for HSPs were found to be associated with many different autoimmune diseases. In models of experimental autoimmunity HSP were found to trigger regulatory T cells and, as a consequence, a modulatory role of HSP in such models was seen. First successes in translating the experimental data into both vaccines and tolerance promoting therapeutic interventions based on HSP have been made or are currently under development. This Special Issue on Heat Shock Proteins and the immune response will offer to readers a fascinating collection of ‘must reads’ for researchers and clinicians in the fields of Immunology, Vaccinology, Rheumatology, and Cancer and Molecular Medicine.
Prof. Dr. W. (Willem) van Eden
Prof. Dr. F. (Femke) Broere
Dr. Arie J. Stoppelenburg
Manuscript Submission Information
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