Biology of Multiple Myeloma: Current Advances and Future Translational Directions
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Medical Biology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 16
Special Issue Editor
Special Issue Information
Dear Colleagues,
During the past two decades, the course of disease in patients with multiple myeloma (MM) has dramatically improved, due to the flood of new treatment modalities with innovative mechanisms of actions. This clinical progress predominantly relies on the results of preclinical and translational science, which has provided important insights into plasma cell biology and MM-specific molecular genetic changes, MM bone marrow niches, inhibition of tumor growth and consequent mechanisms of resistance. However, it seems that current translational science has pointed out just the tip of the iceberg of the MM neoplasia's network, which consists of complex molecular pathways and an entire spectrum of different genetic changes with prognostic significance. The MM biology and natural course of disease have been changed by innovative treatment modalities, acquiring the characteristics of a well-controlled chronic condition. This Special Issue highlights the importance of translational research in MM biology, providing important insights into the MM playground of molecular mechanisms with different prognostic significance, and forthcoming treatment implications.
Prof. Dr. Jelena Bila
Guest Editor
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Keywords
- multiple myeloma
- plasma cell biology
- molecular genetics
- bone marrow microenviroment
- translational research
- prognostic significance
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