Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 61
Special Issue Editors
Interests: natural compounds; antiaging interventions; hallmarks of aging; telomere; epigenetics; autophagy; cellular senescence; cosmeceuticals; nutraceuticals; pharmaceuticals
Special Issue Information
Dear Colleagues,
Natural compounds derived from animals, microbes, and plants represent promising avenues for targeting the aging process by modulating its underlying mechanisms. In this Special Issue, Natural Compounds Targeting 12 Hallmarks of Aging: A Path to Longevity Intervention, we invite submissions that investigate how these compounds can alleviate the biological drivers of aging and serve as potential antiaging interventions. The Special Issue emphasizes the 12 hallmarks of aging—genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis—which collectively contribute to the aging phenotype and chronic disease development. We welcome studies employing diverse systems, including cellular models, 3D or organoid tissues, ex vivo models, and animal studies. In silico or bioinformatic analyses are also accepted, provided that they are substantiated by experimental data. Both original research and review articles are invited; review authors should present expert opinions that extend beyond providing a summary of the existing literature.
Dr. Tawin Iempridee
Dr. Wannita Klinngam
Guest Editors
Manuscript Submission Information
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Keywords
- natural compounds
- antiaging interventions
- hallmarks of aging
- telomere
- epigenetics
- autophagy
- cellular senescence
- pharmaceuticals
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