Molecular Research on Systemic and Periodontal Inflammation
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: 30 July 2027 | Viewed by 87
Special Issue Editor
2. School of Dentistry, Universidad Andres Bello, Santiago 7591538, Chile
Interests: molecular mechanisms of periodontal inflammation; bone regeneration; tissue healing in periodontal and implant-related therapies
Special Issue Information
Dear Colleagues,
Inflammation plays a central role in periodontal and peri-implant tissues, not only in disease processes, but also in the regulation of tissue repair and regeneration. Over recent years, advances in molecular biology and immunology have contributed to a more detailed understanding of the cellular and molecular events that shape inflammatory responses within the oral environment.
In periodontal and peri-implant contexts, inflammation should not be viewed solely as a destructive process. It is also a dynamic and finely regulated response that participates in key aspects of healing. The same signaling pathways that are associated with tissue breakdown are often closely linked to those involved in regeneration, which underscores the need to consider inflammation as a continuum rather than a strictly negative phenomenon.
At the same time, it has become increasingly evident that these processes are influenced by factors that extend beyond the local environment. Systemic inflammatory mediators, the immune status of the host, and the presence of systemic conditions can all modulate periodontal and peri-implant healing and regenerative outcomes. Considering this broader context is therefore important for advancing both research and clinical practice.
This Special Issue aims to gather contributions that explore the role of inflammation in periodontal and peri-implant regeneration from a molecular and translational perspective. We are particularly interested in studies that address inflammatory signaling pathways, host–microbiome interactions, and the biological mechanisms underlying tissue repair. Submissions that incorporate emerging approaches, such as transcriptomics, proteomics, or other omics-based strategies, as well as studies on immune-modulatory biomaterials, are especially welcome.
We welcome original research articles, mechanistic and translational studies, as well as systematic reviews and short communications that provide relevant insights into these areas.
The intention of this Special Issue is to bring together different perspectives that contribute to a more integrated understanding of how inflammation shapes periodontal and peri-implant regeneration, and how this knowledge can be translated into more effective and biologically grounded therapeutic strategies.
Dr. Franco Cavalla
Guest Editor
Manuscript Submission Information
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Keywords
- periodontal inflammation
- peri-implant inflammation
- molecular signaling
- immune regulation
- bone regeneration
- periodontal regeneration
- inflammatory pathways
- host–microbe interaction
- oral tissue healing
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