Advances in Microseparation Technology
A special issue of Bioengineering (ISSN 2306-5354).
Deadline for manuscript submissions: closed (30 September 2018) | Viewed by 11140
Special Issue Editor
Interests: biologics and botanical manufacturing technology; green technology; digital twins and process analytical technology under quality by design
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues
Needs in novel white and red biotechnology process applications, which are derived from large social needs related to, e.g., the bio-based world and innovative medicine initiatives, are causing new challenging separation tasks of high volume/low cost, as well as low volume/high value products at a reduced cost-of-goods. Therefore, improvements in efficient downstream processing technologies for biotechnology process development and manufacturing are still key-issues under research and development. Process intensification focuses on process integration using consistent design methods for hybrid separations and optimal total process integration methods, based on process modeling, as well as process enhancement activities, such as micro-/milli-structured devices, ultra-sound, microwave, pulsed-electric-field enhances mass transfer and/or novel separation media, e.g., nano-scaled and/or selectivity/capacity enhanced.
Recently, micro-/milli-structured devices have been invented and characterized for different process applications, such as chromatography, membranes, precipitation/crystallization, as well as liquid–liquid extraction and distillation. Novel media have been introduced and mass transfer enhancing energy input described.
Nevertheless, further activities are needed to make design methods, materials and devices more applicable for the community in order to speed up industrialization. Especially in regulated industries, any change in process development and manufacturing technology has to be convincing for regulatory authorities and, therefore, applicants based on sound scientific methods related to consistent transparent data-driven decisions.
This Special Issue will help to bridge the gap between fundamental academia research and industrial utilization. Therefore, any contributions related to the above-mentioned topics and applications are welcome.
Prof. Dr. Jochen Strube
Guest Editor
The first round submission deadline: 30 September 2017
Manuscript Submission Information
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Keywords
- Biotechnology
- Process Intensification
- Micro Technology
- Downstream Processing
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