Extracellular Vesicles: From Biology to Biomedical Applications
A special issue of Bioengineering (ISSN 2306-5354).
Deadline for manuscript submissions: closed (30 November 2018) | Viewed by 64459
Special Issue Editors
Interests: extracellular vesicles; biosensors and bioanalytics; nanomaterial sensors
Special Issues, Collections and Topics in MDPI journals
Interests: extracellular vesicles; enrichment; ultracentrifugation; nanoparticle tracking analysis; lateral flow immunoassay
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Extracellular Vesicles (EVs) are cell-derived membranous structures with great potential as a source of biomarkers. They are released by all types of cells into the extracellular environment. To date, EVs have been isolated from different body fluids; however, the elucidation of their biogenesis and roles are still a challenge. Since they are not associated to a single disease, it could be considered that the biomedical research in this field is still at the initial steps. They have been acknowledged as target for diagnosis and prognosis of several diseases, through their protein and RNA cargo. Understanding the EV targeting would open the paths for novel therapeutic routes. Progress in the field is currently limited by the available techniques for their characterization and quantification. The last meeting of the International Society for Extracellular Vesicles 2018 has highlighted the need for strong bioengineering solutions for their isolation and analysis. Specific challenges include establishing the heterogeneity of EV population, simplification of the analytical protocols and single EV analysis.
This Special Issue focuses on updated techniques recently developed to meet these objectives. It is expected that the availability of new methods and platforms would speed up biological research and trigger medical applications.
Dr. María Carmen Blanco-López
Dr. Esther Serrano-Pertierra
Guest Editors
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