Extracellular Matrix Biomaterial for Tissue Engineering and Regenerative Medicine
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 709
Special Issue Editors
Interests: extracellular matrix; tissue engineering; tumor microenvironment; stem cells; breast cancer
Interests: 3D bioprinting; photo-crosslinkable biomaterials; extracellular matrix; breast cancer; microphysiological systems; microfluidics
Special Issue Information
Dear Colleagues,
The development of benchtop models and superior biomaterials that better recapitulate native conditions is of critical importance for more accurate disease modeling and tissue engineering applications. Key components of native tissue can include stromal cells, the extracellular matrix (ECM), and surrounding signaling molecules. Chief among the components is the ECM, composed of several classes of macromolecules that are each responsible for balancing the physical and chemical composition. The ECM’s topography (fiber diameter and orientation) plays a critical role in cell adhesion, migration, and proliferation, with changes leading to mechanical stimuli altering signaling pathways. Changes in protein composition and matrix stiffness have also been identified when tissue undergoes trauma or disease. This Special Issue, entitled “Extracellular Matrix Biomaterial for Tissue Engineering and Regenerative Medicine”, is focused on recent advancements in investigating the properties of the extracellular matrix and developing tools to recapitulate in vivo properties for use within tissue engineering and regenerative medicine applications.
The scope of this Special Issue includes, but is not limited to, the following topics:
- Novel methods to generate, isolate, and characterize the ECM;
- ECM protein distribution or changes;
- Disease modeling using native ECMs;
- Engineered biomaterials;
- Three-dimensional biofabrication methods;
- New technologies for synthetic materials to mimic native tissue.
Bringing together experts across different disciplines is paramount for the field to continue to develop and further increase its scientific impact.
Dr. Elizabeth C. Martin
Dr. Jorge Alfonso Belgodere
Guest Editors
Manuscript Submission Information
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Keywords
- extracellular matrix
- ECM protein
- biomaterials
- 3D bioprinting
- tissue engineering
- regenerative medicine
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