Engineering Biomaterials for Regenerative Medicine Applications

Dear Colleagues,

There is emerging interest in the innovation of biomaterials used in medical applications designed to interact with various biological systems. They are used in various applications, including implants, drug delivery systems, therapeutic models, and tissue engineering scaffolds. Biomaterials are used in regenerative medicine to create scaffolds that provide a temporary structure for cells to grow and develop into new tissue regeneration. The scaffold can be made from various materials, including natural polymers, synthetic polymers, and other material platforms. The choice of material depends on the specific application. For example, natural polymers, such as collagen, chitosan, cellulose, gelatin, alginate, silk fibroin, and starch, alone or in combination, are widely used to create scaffolds for soft tissue engineering applications. Synthetic polymers, such as polylactic acid (PLA), Polylactic-co-glycolic acid (PLGA), and polyglycolic acid (PGA), are often used to create scaffolds for hard tissue engineering applications. Metal nanostructures, such as iron, gold, zinc, etc., often create scaffolds for bone tissue engineering applications. In addition, biomaterials can be used to improve the success of regenerative medicine therapies in several ways. They can provide a temporary structure for cells to grow and develop, deliver cells to the target site, and provide a controlled release of growth factors and other signaling molecules. Biomaterials are an important part of the future of regenerative medicine applications. As the field continues to develop, biomaterials will play an increasingly important role in developing innovative therapies for various diseases and conditions.

Here are some topics of interest that this Special Issue is focusing on:

• Artificial skin: Papers report the biomaterials used to create artificial skin that can be used to treat burns and other skin injuries.
• Artificial cartilage: Papers report the biomaterial used to create artificial cartilage that can replace damaged cartilage in the knee, hip, and other joints.
• Artificial bone: Papers report the biomaterial used to create artificial bone that can replace damaged bone in the spine, skull, and other bones.
• Tissue engineering: Papers report the biomaterials used to create scaffolds that can be seeded with cells to grow new tissue. This is being used to develop new treatments for a variety of conditions, including heart disease, stroke, and spinal cord injury.
• Drug delivery: Papers on the interest in biomaterials use in drug delivery to tumors in a controlled and targeted manner.
• Immunotherapy: Papers focus on biomaterials that can deliver immune cells to tumors, which can help stimulate the body's immune system to fight cancer.
• Tissue engineering: Papers use biomaterials to create scaffolds that can be seeded with cells to grow new tissue to replace damaged tissue caused by cancer.
• Diagnostics: Biomaterials applications to develop new diagnostic tools that can help identify cancer early when it is most treatable.

In the future, biomaterials will be a promising new frontier in regenerative medicine. As the field continues to develop, biomaterials will play an increasingly important role in developing new therapies for various diseases and injuries. As the field of regenerative medicine continues to evolve, biomaterials will play an increasingly important role in the development of new treatments.

Dr. Ramar Thangam
Dr. Heemin Kang
Dr. Venugopal Krishnan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomaterials
• tissue repair
• regenerative medicine
• stem cells
• immune cells
• cancer therapy
• biomedical devices and implants
• tissue regeneration