Recent Advance in Biomaterials for Bone Tissue Regeneration
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 2060
Special Issue Editor
Special Issue Information
Dear Colleagues,
Biomaterials are being developed in terms of surface modifications, composite materials, advanced surgical allografts and bone graft substitutes so that they can be used in bone tissue regeneration. Many studies have uncovered the mechanisms behind augmented bone healing, thereby promoting the collective understanding of arthrodesis and bone apposition. The traditional metals used in implantable medical devices for bone healing, either as an internal fixator or a part of an implant, are now processed with new additive manufacturing techniques. Thus, these internal fixators, complemented with the use of biomaterials, can now be found with modified surfaces that alter the cellular response. Recently, use of polymers that incorporate textured metal surfaces has also been suggested to increase the bone implant interface strength. Such modifications include a macroscopic scale feature to prevent expulsion and migration and microscale changes that facilitate bone ongrowth. These novel bone growth substitutes form a new category of synthetic bone healing materials, such as bioglass or calcium phosphates.
New processing techniques with additive manufacturing create an opportunity to produce a tailored bone implant interface while maintaining the structural properties found in hardware such as plates and screws. The role of the substrate as an osteoconductive surface has also been dramatically enhanced with the development of biomaterials. Furthermore, osteobiologics, used as surgical allografts, have also benefitted from advancements in the processing techniques.
To highlights these emerging research areas of bone healing, this Special Issue invites submissions of manuscripts dedicated to the use of biomaterials in bone tissue regeneration.
Prof. Dr. Boyle Cheng
Guest Editor
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