Advances in Polymer & Composite Biomaterials for Biomedical Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: closed (20 September 2022) | Viewed by 3358

Special Issue Editors


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Guest Editor
Division of Mathematics and Engineering Sciences, Department of Military Sciences, Hellenic Army Academy, 16673 Vari, Greece
Interests: molecular spectroscopy; Raman spectroscopy; multifunctional materials; antiballistic materials
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Guest Editor
National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece
Interests: nanotechnology; conjugated polymer nanoparticles; bioimaging; thin films; electrochemical sensors; laser-matter interaction

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Guest Editor
1. Department of Surveying and Geoinformatics Engineering, School of Engineering, University of West Attica, 122 44 Egaleo, Greece
2. Department of Mathematics and Engineering Sciences, Hellenic Army Academy, Evelpidon Avenue, 166 72 Vari Attika, Greece
Interests: construction materials; nanoparticles; nanocements; materials characterization; structural analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Composite materials are now established as an essential part of our technological advances, and our practical applications, due to their outstanding mechanical response and tailor-made properties. Polymer composites are nowadays, a well-recognized family of composites, characterized by ease in manufacture, low cost, established processing methods, and varied applications ranging from daily-use issues to highly complicated electronics and advanced medical combinations. Also, nanocomposites made available with graphene and other types of advanced ceramic or organic nanoparticles, are into play in the late years.

This special issue shall focus on the most important fabrication techniques for polymers and polymer- composites in biomedical applications such as electrospinning, melt-extrusion, solution mixing, and melt spinning technologies, as well as in situ methods. Additive manufacturing techniques, such as various 3D printing methods, which have also facilitated the use of smart polymers and some types of filled composites in the families of medical technologies are also of great interest.

Finally, recent progress in biomedical applications and technologies are promoted, such as tissue engineering (including bone, blood vessels, oral tissues, and skin), maxillofacial, plastic surgery, dental resin-based composites, and wound dressing -healing materials as well as smart bio-implants.

Prof. Dr. Dionysis E. Mouzakis
Dr. Nektarios Nasikas
Dr. Panagiota Koralli
Dr. Styliani Papatzani
Guest Editors

Manuscript Submission Information

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Keywords

  • composites in biomedical applications
  • bio-nano-composites
  • smart composites in biomedical applications
  • biopolymer composites
  • composite polymer scaffolds for tissue engineering

Published Papers (2 papers)

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Research

11 pages, 4208 KiB  
Article
3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters
by Libing Zhu, Manzhou Zhang, Xincheng Xiang and Xiangang Wang
Appl. Sci. 2022, 12(19), 9839; https://doi.org/10.3390/app12199839 - 29 Sep 2022
Viewed by 1113
Abstract
Proton pencil beam scanning is a dynamic beam delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and scanning positions will have a significant effect on the delivered dose distribution. We employed polymer gel dosimeters to measure the [...] Read more.
Proton pencil beam scanning is a dynamic beam delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and scanning positions will have a significant effect on the delivered dose distribution. We employed polymer gel dosimeters to measure the spot size and the scanning positions for the Shanghai Advanced Proton Therapy facility (SAPT). Polymer gel dosimeters (MAGAT-f and PAGAT) were utilized to measure the full width at half maximum (FWHM) of the beam spot at various depths on the basis of their MRI readouts. The correlation between the spot FWHM and standard deviation (σ) was analyzed at different depths. The measured Bragg peak range was compared with the Monte Carlo (MC) simulation. Three-dimensional volume rendering of the Bragg peak was reconstructed for the 3D visualization to measure the spot size three-dimensionally. The R2 dose–response curve was investigated with polymer gel dosimeters. The deviations of the Bragg peak ranging between measurement and simulation were 0.13% and −0.53% for MAGAT-f and PAGAT, respectively. Our results ascertain the feasibility of a polymer gel dosimeter to measure the spot size and positions of a proton pencil beam. Full article
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12 pages, 408 KiB  
Article
Safety and Efficacy of Modern Stents in Patients with Metabolic Syndrome
by Priscilla Pașc, Luciana Dobjanschi, Mihaela Zdrîncă, Marcel Zdrîncă, Liana Ștefan, Carmen Anca Huniadi, Marieta Lestyan, Florina Miere (Groza) and Mircea Ioachim Popescu
Appl. Sci. 2022, 12(7), 3277; https://doi.org/10.3390/app12073277 - 23 Mar 2022
Cited by 3 | Viewed by 1515
Abstract
The impact of metabolic syndrome (MS) on stent performance and outcomes of patients underwent percutaneous coronary intervention (PCI), including stent implantation, had not yet been fully established. The aim of the present study was to investigate long-term safety and efficacy of 2nd generation [...] Read more.
The impact of metabolic syndrome (MS) on stent performance and outcomes of patients underwent percutaneous coronary intervention (PCI), including stent implantation, had not yet been fully established. The aim of the present study was to investigate long-term safety and efficacy of 2nd generation DES vs. other stent types in MS patients underwent successful PCI for an acute coronary event. Descriptive epidemiology, angiographic characteristics and one-year clinical outcomes, including major adverse cardiovascular events (MACE) and target lesion revascularization (TLR) procedures were evaluated according to the stent type inserted for 204 patients. The occurrence of TLR (6.62% vs. 9.43%, p = 0.50) and the composite outcomes (20.52% vs. 24.52%, p = 0.54) did not differ significantly between patients having 2nd generation drug eluting stents (DES) or other stent types implanted at the index procedure. It seems that the PCI in acute coronary syndrome (ACS) is similarly efficient regardless of the stent type, suggesting that for the treatment of ACS in MS patients, all stent types show similar results, in terms of TLR or MACE. Full article
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