Application of Nanomaterials/Nanotechnology in Analytical Chemistry

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: closed (21 November 2022) | Viewed by 2985

Special Issue Editors


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Guest Editor
Department of Chemistry, SAPIENZA Università di Roma, P.le A. Moro 5, 00185 Rome, Italy
Interests: liquid chromatography–mass spectrometry; mycotoxins; environmental contaminants; food contaminants; polyphenols; sample preparation; metabolomics; peptidomics; bioactive peptides
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Chemistry, SAPIENZA Università di Roma, P.le A. Moro 5, 00185 Rome, Italy
Interests: analytical chemistry; sample preparation; liquid chromatography; mass spectrometry; proteomics; lipidomics; metabolomics; analytical method development; post-translational modifications of protein analysis; small molecule analysis for environmental and food analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Analytical chemistry has been changing significantly over the last decades, because of the technological developments in different fields. As such, analytical techniques greatly benefitted from the development of nanotechnology, as nanoparticles and nanotools are continuously attracting attention in nanotechnological-based analytical processes. More specifically, nanomaterials are greatly impacting the process of sample preparation, in a variety of applications, from environmental and food analysis, to bioanalytical applications. The use of nanotechnologies in analytical chemistry is also important for answering the urgent call for environmentally friendly processes to comply with green chemistry requirements, as they allow for the development of miniaturized sample preparation methods, such as microextraction techniques; advanced solid-phase extraction materials; and the development of devices suitable for sensor and biosensor creation. The versatility and derivatization potential of nanomaterials is also fundamental for the development of new materials with an enhanced selectivity for the target analytes, with an improved clean-up efficacy, which, in turn, improves the sensitivity of the complete analytical method.

In this context, the aim of the Special Issue “Application of Nanomaterials/Nanotechnology in Analytical Chemistry” is to provide a snapshot of the current state of the art in the use of nanomaterials in analytical chemistry.

Prof. Dr. Chiara Cavaliere
Dr. Susy Piovesana
Guest Editors

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Keywords

  • sample preparation
  • nanomaterials
  • nanotechnology
  • sensors
  • analytical chemistry
  • biosensors

Published Papers (1 paper)

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Research

16 pages, 3154 KiB  
Article
A Systematic Comparative Study of the Toxicity of Semiconductor and Graphitic Carbon-Based Quantum Dots Using In Vitro Cell Models
by Maria Carmen Navarro-Ruiz, Angelina Cayuela, María Laura Soriano, Rocio Guzmán-Ruiz, Maria M. Malagón and Miguel Valcárcel
Appl. Sci. 2020, 10(24), 8845; https://doi.org/10.3390/app10248845 - 10 Dec 2020
Cited by 5 | Viewed by 1775
Abstract
A comparative, fully parallel study of nanoparticles (NPs) toxicity by in vitro cell viability is shown looking for reliable comparability of nanotoxicological results, a well-recognized bottleneck in the context. This procedure is suitable to compare toxicity of similar NPs, as well as the [...] Read more.
A comparative, fully parallel study of nanoparticles (NPs) toxicity by in vitro cell viability is shown looking for reliable comparability of nanotoxicological results, a well-recognized bottleneck in the context. This procedure is suitable to compare toxicity of similar NPs, as well as the influence on toxicity of the size, surface, and other characteristics. As a case of study, semiconductor (SQDs) and graphitic-carbon quantum dots (CQDs) with identical surface groups and size were evaluated. All experiments were conducted at same conditions, involving two types of cells (mouse fibroblasts (3T3-L1) and carcinoma human hepatocellular cells (HepG2)) and different extracellular components (in the absence or presence of fetal bovine serum (FBS)). Cell viability demonstrated the excellent biocompatibility of CQDs compared to SQDs, which caused higher percentage of cell death at lower concentrations, as predicted but never clearly demonstrated. However, our comparative studies established that the toxicity of SQDs and CQDs are cellular type-dependent, and the absence or presence of serum proteins reduces the minimal concentration necessary of NPs to produce toxicity. Full article
(This article belongs to the Special Issue Application of Nanomaterials/Nanotechnology in Analytical Chemistry)
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