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Bioactive Compounds in Medical, Pharmaceutical and Cosmetic Sciences

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 741

Special Issue Editor


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Guest Editor
Department of Pharmacy, University of Araraquara (UNIARA), Rua Carlos Gomes, 1338-Centro Araraquara, São Paulo 14801-340, Brazil
Interests: pharmacy; pharmacotechnics; cosmetology; cosmetics

Special Issue Information

Dear Colleagues,

The use of bioactive compounds, which are obtained from a wide variety of sources, has a long history. Their beneficial use is still observed today, with scientific evidence already published for many compounds. However, further research is still required. The medical, pharmaceutical and cosmetics sectors are currently assessing these compounds, but further studies are needed on compounds already in use, opening the possibility for new discoveries.

This Special Issue aims to provide an updated collection, demonstrating new findings regarding the use of these bioactive compounds in the health field. We are pleased to invite you to contribute your extensive knowledge to this Special Issue.

Suggested themes and article types for submissions:

Original research articles and reviews are welcome in this Special Issue. Research areas may include (but are not limited to) the following:

  1. Plant bioactives used in medicine;
  2. Plant bioactives used in pharmacy;
  3. Plant bioactives used in cosmetology;
  4. Bioactives of animal origin used in medicine;
  5. Bioactives of animal origin used in pharmacy;
  6. Bioactives of animal origin used in cosmetology;
  7. Bioactives of mineral origin used in medicine;
  8. Bioactives of mineral origin used in pharmacy;
  9. Bioactives of mineral origin used in cosmetology;
  10. Screening of new bioactive compounds for use in healthcare.

We look forward to receiving your contributions.

Dr. Bruna Chiari-Andréo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant compounds
  • compounds of animal origin
  • health sciences
  • efficacy
  • safety
  • chemical composition

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Published Papers (1 paper)

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23 pages, 2724 KB  
Systematic Review
Preclinical Therapeutic Potential of Peristrophe roxburghiana: A Systematic Review and Meta-Analysis
by Le Thi Nhu Ngoc and Young-Chul Lee
Appl. Sci. 2026, 16(4), 2041; https://doi.org/10.3390/app16042041 - 19 Feb 2026
Viewed by 467
Abstract
This systematic review and meta-analysis assessed the preclinical therapeutic potential of Peristrophe roxburghiana extracts (PREs). Among the 46 screened articles, 12 met the inclusion criteria and were quantitatively analyzed. The pooled standardized mean differences (SMDs) between the PRE treatment and control groups were [...] Read more.
This systematic review and meta-analysis assessed the preclinical therapeutic potential of Peristrophe roxburghiana extracts (PREs). Among the 46 screened articles, 12 met the inclusion criteria and were quantitatively analyzed. The pooled standardized mean differences (SMDs) between the PRE treatment and control groups were calculated to investigate the antioxidant, biocompatible, anticancer, and antihypertensive effects. PRE exhibited measurable antioxidant activity, with low pooled IC50 values for DPPH (3.57 [0.96; 13.34] μg/mL), ABTS (91.96 [47.30; 178.78] μg/mL), and FRAP (63.39 [0.29; 13,992] μmol Fe2+/g extract). Biocompatibility analyses did not indicate a statistically significant reduction in the viability of normal cell lines. By contrast, the PRE treatment was associated with reduced cell viability in cancer cells (SMD = 2.28 [0.54, 4.03], I2 = 63%). PRE treatment effectively improved the pathological outcomes in L-NAME-induced hypertensive rat models, including reductions in blood pressure parameters and favorable modulation of oxidative stress-related biomarkers. Although several comparisons showed substantial heterogeneity, subgroup and meta-regression analyses identified differences in the methodological approaches (extraction methods, raw materials, and geographical regions) as major contributors. Overall, these findings support the preclinical therapeutic potential of PREs and provide a scientific basis for future mechanistic and clinical studies. Full article
(This article belongs to the Special Issue Bioactive Compounds in Medical, Pharmaceutical and Cosmetic Sciences)
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