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Advances in Phytochemicals: Extraction, Isolation, and Identification

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Chemical and Molecular Sciences".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 164

Special Issue Editor


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Guest Editor
Department of Inorganic Chemistry, Physical Chemistry and Electrochemistry, Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology POLITEHNICA Bucharest, Bucharest, Romania
Interests: food; toxicology; natural products; phytochemistry; bioactive substances; antioxidants; volatile oils; chromatography; mass spectrometry; UV–Vis spectroscopy; infrared spectroscopy; environmental chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is devoted to the most recent scientific advances regarding the extraction, isolation, and identification of phytochemicals. Phytochemicals are natural compounds of plant origin and comprise very diverse chemical classes, including carotenoids, polyphenols, alkaloids, terpenes and terpenoids, phytosterols, saponins, glucosinolates, anthocyanins, tannins, flavonoids, stilbenoids, polyacetylenes, and cuticular waxes, among others. Many of these have important biological activities not only in plants, where they serve as either primary or secondary metabolites, but also as part of human-targeted pharmaceuticals, nutraceuticals, or dietary supplements, e.g., atropine, quercetine, berberine, bromelain, curcumin, cannabidiol derivatives, etc. The separation and isolation of such valuable compounds from plant material are typically carried out by using extractive methods, which can be classical (solvent-based) or modern (ultrasound, microwave, supercritical fluid-based), and are often followed by sequential purification operations usually involving one or several versions of chromatography (CC, TLC, HPLC, and/or GC). After purification, the phytochemical is identified based on either the available literature, or, if novel, its structure is elucidated using an array of analytical methods, amongst which are NMR and mass spectrometry, UV–Vis, IR, and Raman spectroscopy, X-ray crystallography, and circular dichroism in cases where chiral compounds are expected. We welcome original research articles, literature reviews, and short communications on any recent developments in phytochemical research, such as those mentioned above, but not exclusively limited to them.

Yours sincerely,

Dr. Radu Racovita
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant natural products
  • extraction methods
  • isolation and purification
  • structure elucidation
  • nuclear magnetic resonance
  • mass spectrometry
  • circular dichroism
  • X-ray crystallography
  • spectroscopy
  • chromatography

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