In Silico Modeling of Human Organ Functions: Advances and Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 35
Special Issue Editor
Interests: physiology simulations; analysis of movement in sports and rehabilitation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue explores cutting-edge computational approaches for modeling human organ functions and processes, showcasing their practical applications across medicine, drug development, and personalized healthcare. We welcome original research and review articles that demonstrate innovative in silico techniques—spanning molecular dynamics, machine learning, agent-based models, multi-scale integration, and digital twin technologies—that accurately simulate physiological and pathological behaviors within human organs. Of particular interest are studies that bridge theoretical modeling with experimental validation, showcase clinical applications in disease prediction and treatment optimization, advance methodologies for integrating multi-omics data into organ models, and address current challenges in computational organ modeling. This collection aims to highlight how computational modeling is transforming our understanding of human organ functions while accelerating therapeutic innovations and precision medicine approaches.
Dr. Alexandros Alexopoulos
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- in silico simulation
- molecular dynamics approaches
- physiological and pathological simulation
- therapeutic optimization
- computational drug discovery
- multi-omics data integration
- AI-driven biomedical
- precision medicine
- diagnostic models
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
