Therapeutic Ultrasound Across Scales: From Cellular Models to Clinical Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".
Deadline for manuscript submissions: 20 July 2026
Special Issue Editors
Interests: therapeutic ultrasound; regenerative medicine; ultrasound imaging; targeted drug delivery
Special Issues, Collections and Topics in MDPI journals
Interests: therapeutic ultrasound; nanoparticle-based theranostics; drug delivery; ultrasound; preclinical models; molecular imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Therapeutic ultrasound has become a powerful modality in modern medicine, enabling precise, non-invasive interventions that modulate biological processes at the cellular and tissue level. This Special Issue, “Therapeutic Ultrasound Across Scales: From Cellular Models to Clinical Applications,” aims to highlight recent advances, emerging methodologies, and translational approaches that bridge the gap between laboratory studies and clinical practice.
We invite contributions that explore the multifaceted roles of ultrasound as a therapeutic and modulatory tool across biological systems. Topics of interest include, but are not limited to, the following:
- High-intensity ultrasound (e.g., thermal ablation, focused ultrasound surgery);
- Low intensity pulsed ultrasound (e.g. regenerative medicine, triggered drug and gene delivery);
- Ultrasound and acoustic cavitation technologies for the enhancement of neurotherapies;
- Non-invasive acoustic modulation of neural cells;
- Next-generation technologies for advancing ultrasound therapies from preclinical research to clinical practice;
- High-precision ultrasound approaches for cellular applications;
- Mechanistic studies of ultrasound–tissue and ultrasound–cell interactions in in vitro models;
- Integration of ultrasound with imaging, nanotechnology, and regenerative medicine for enhanced therapeutic efficacy;
- Ultrasound-guided therapeutic intervention.
This Special Issue welcomes high-quality original research articles, reviews, and short communications that advance our understanding of therapeutic ultrasound from fundamental mechanisms to clinical applications. By fostering interdisciplinary dialogue among physicists, engineers, biologists, and clinicians, this collection seeks to provide a comprehensive overview of current trends and future directions in the field of therapeutic ultrasound.
Dr. Andrea Cafarelli
Dr. Allegra Conti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- therapeutic ultrasound
- high-intensity focused ultrasound (HIFU)
- low-intensity pulsed ultrasound (LIPUS)
- ultrasound-mediated drug delivery
- ultrasound bioeffects
- acoustic neuromodulation
- thermoablation
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