Antimicrobial Peptides: Synthesis, Properties and Applications

Dear Colleagues,

The urgency of finding new antimicrobial drugs is obvious if we consider the 10 million premature deaths estimated by 2050 due to antibiotic resistances (AMR) [O’Neill, J. 2014].

Antimicrobial peptides (AMPs) have appeared as an alternative to the commonly used antibiotics due to their antimicrobial, antifungal, and antiviral activities. Widening the knowledge in this field could have a big impact on the AMR issue.

The aim of this Special Issue is to gather scientific articles (research articles, review articles, as well as short communications) related to:

• New natural AMPs with special properties (e.g. immunomodulatory properties, prevention of the biofilm formation, prevention of post-surgical adhesion);
• AMPs designed using knowledge of natural AMPs (structure-based, AMP libraries, selective AMPs);
• Mechanisms of action of AMPs (molecular targets of AMPs, mechanism of membrane disruption);
• Potential clinical applications of AMPs.

All together, the papers published in this Special Issue should widen our AMP knowledge, serving as inspiration in the discovery of new antibacterial drugs.

Prof. Dr. Enea Sancho-Vaello
Prof. Dr. Kornelius Zeth
Guest Editors

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