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Recent Advances in Musculoskeletal Rehabilitation and Treatment

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 October 2026 | Viewed by 1465

Special Issue Editors


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Guest Editor
Department of Orthopaedic and Trauma Surgery, Casa di Cura di Bernardini, 74121 Taranto, Italy
Interests: shoulder; shoulder arthroscopy; knee arthroplasty

Special Issue Information

Dear Colleagues,

Musculoskeletal diseases are a wide range of conditions affecting bones, muscles, joints, and connective tissues. Musculoskeletal disorders are frequently associated with significant levels of suffering in adults and are the leading causes of global disability and health burden. The etiology of these diseases can significantly vary, including genetic predisposition, overuse injuries, autoimmune disorders, and age-related degeneration. Persistent pain resulting from musculoskeletal disorders may also lead to long-term psychological consequences, as well as a significant societal burden due to the high associated healthcare costs and their effect on workforce availability. Treatment goals for musculoskeletal conditions include reduced pain, joint protection, and improved function and quality of life (QoL). The treatment strategies can use many resources available to treat musculoskeletal pain and limitations: exercise, medication, physical modalities, adaptive equipment, and arthritis education, including self-help and support groups. Current interventions have shown limited effectiveness, which is highlighted by small to moderate effect sizes and limited evidence of their effectiveness in the long term. Strong recommendations for education and patient self-management have been made as the first-line treatment options for musculoskeletal disorders. Education interventions, including basic information on pain and available management options, exercise, activity modification, and the importance of healthy lifestyle choices, represent a solid foundation for managing musculoskeletal problems. The treatment of musculoskeletal diseases is undergoing significant innovation with the advent of new technologies. Digital health solutions, such as mobile apps and wearable devices, are increasingly integrated into rehabilitation and management strategies.

Advances in Musculoskeletal Rehabilitation and Treatment hold great potential to progress the field of rehabilitation sciences by identifying novel techniques and methodologies to reduce error, eliminate medical referrals, and accurately predict consequential health outcomes.

Dr. Raffaello Pellegrino
Dr. Rocco Aicale
Guest Editors

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • education
  • exercise
  • rehabilitation
  • weight loss
  • telerehabilitation
  • pain
  • physical therapy
  • regenerative treatment

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Published Papers (1 paper)

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Research

16 pages, 884 KB  
Article
Comparisons Between Frail and Non-Frail Hospitalized Patients in Muscle Strength and Range of Motion After Hip Fracture Surgery: A Single-Blind Experimental Study
by Ilektra Sidiropoulou, Anastasios Vavvas, Konstantinos Karzis, Christos Garnavos, Dimitrios Chytas and Anna Christakou
Appl. Sci. 2025, 15(23), 12602; https://doi.org/10.3390/app152312602 - 28 Nov 2025
Viewed by 852
Abstract
Frailty has emerged as a critical determinant of clinical outcomes in elderly patients, shaping postoperative recovery in crucial orthopedic events, such as hip fractures. The purpose of the present study is to examine the impact of frailty syndrome on muscle strength and joint [...] Read more.
Frailty has emerged as a critical determinant of clinical outcomes in elderly patients, shaping postoperative recovery in crucial orthopedic events, such as hip fractures. The purpose of the present study is to examine the impact of frailty syndrome on muscle strength and joint range of motion in the non-fractured lower extremity and upper extremities of hospitalized older adults following hip fracture surgery. The sample consisted of 60 elderly patients recovering from either intracapsular or extracapsular hip fractures. Participants were categorized into either a frail or non-frail group, determined by the Clinical Frailty Scale. The outcome measures of muscle strength and range of motion of the upper and lower extremities were assessed by valid instruments, including a hand-held dynamometer, the Medical Research Council scale, and a digital goniometer. Statistical comparisons between groups were conducted using the independent samples t-test and the Mann–Whitney U test. The results showed that the non-frail group demonstrated greater active range of motion in the shoulder bilaterally (right: t = −2.85, left: U = 628.00, p < 0.05), elbow flexion bilaterally (right: U = 589.50, left: U = 592.50, p < 0.05), hip flexion (U = 679.50, p < 0.01), knee extension (t = −3.07, p < 0.05), and ankle dorsiflexion (t = −2.36, p < 0.05). Regarding the muscle strength, the non-frail group showed significantly higher grip strength bilaterally (right: U = 754.50, left: U = 713.50, p < 0.001), as well as greater strength in hip flexion (U = 641.00, p < 0.01) and ankle dorsiflexion (U = 619.50, p < 0.01). Frailty may negatively influence the muscle strength and joint mobility in non-fractured extremities, thereby hindering postoperative physical recovery in older adults with hip fractures. Further research involving a larger and more homogeneous sample may predict falls in elderly patients after hip or knee surgery using the Clinical Frailty Scale. Full article
(This article belongs to the Special Issue Recent Advances in Musculoskeletal Rehabilitation and Treatment)
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