Oxidative Stress and Fetal-Maternal Health

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: closed (15 November 2021) | Viewed by 447

Special Issue Editors


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Guest Editor
1. Ageing and Stress Group, Instituto de Investigação e Inovação em Saúde (I3S), Porto, Portugal
2. Department of Immuno-Physiology and Pharmacology, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto, Portugal
Interests: oxidative stress; reproductive aging; fertility decline; placentation; cell senescence; pregnancy-related complications; fetal development

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Guest Editor
1. Unit of Experimental Biology, Department of Biomedicine, Faculdade de Medicina da Universidade do Porto (FMUP), Porto, Portugal
2. Ageing and Stress Group, Instituto de Investigação e Inovação em Saúde (I3S), Porto, Portugal
Interests: oxidative stress; obesity and age-related degenerative conditions; reproductive aging; fertility decline; placentation; cell senescence; pregnancy-related complications; fetal development

Special Issue Information

Dear Colleagues,

Redox balance plays a pivotal role in the modulation of physiological processes fundamental to reproduction, as spermatogenesis, folliculogenesis, fertilization, decidualization for blastocyst implantation, implantation, placenta development, and embryogenesis, whereas its loss impinges on fertility and pregnancy success.

When the balance between reactive oxygen species (ROS) production and its scavenging is disrupted, a state of oxidative stress (OS) arises. Under such conditions, oxidation-dependent cell signaling networks become dysregulated and oxidation of DNA, lipids, and proteins is increased, leading to progressive cell dysfunction. This process has been proposed to underlie aging and susceptibility to a variety of disorders; in addition, it has been recognized to contribute to some of the most serious obstetrical conditions originating at the maternal/ fetal interface, with dire consequences for both fetal and maternal health.

In this Special Issue, researchers are invited to contribute with experimental or review manuscripts aiming to highlight and unravel mechanisms by which OS contributes to the development of pregnancy-related pathologies with impact on maternal and fetal health and new pharmacological approaches that may target OS and improve pregnancy outcome. 

Prof. Dr. Elisabete Silva
Prof. Dr. Henrique Almeida
Guest Editors

Manuscript Submission Information

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Keywords

  • Oxidative stress
  • Pregnancy-related complications
  • Fetal development

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Published Papers

There is no accepted submissions to this special issue at this moment.
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