Antibody Engineering

Dear Colleagues,

Antibody engineering has revolutionized the current generation of antibodies, which are needed for detection of proteins, analysis and inhibition of protein functions, as well as diagnostic and therapeutic purposes. Human, chimeric and humanized antibodies with high specificity and affinity can now be generated by antibody engineering. Chimeric or humanized variants of mouse antibodies are applied in the clinic. Fusion of antibodies with cytokines, immunotoxins, specific Fc receptors and different signal peptides can be engineered. Phage display of large collections of antibody fragments enables the selection of specific antibodies in vitro. Many human antibodies selected by phage display are being studied and are showing promise in clinical trials.

This Special Issue on antibody engineering will present new technology developments and in vitro and in vivo applications of new engineered antibodies. Researchers will present their latest results and Review articles will cover new developments in the field.

Dr. Thomas Böldicke
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.