Novel Strategies and Technologies for the Development of Tumor-Specific Antibodies
A special issue of Antibodies (ISSN 2073-4468). This special issue belongs to the section "Antibody Discovery and Engineering".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 33327
Special Issue Editor
Special Issue Information
Dear Colleagues,
In this Special Issue, we aim to compile a set of references and techniques that will support the generation of antibodies specific to tumor targeting and that fulfill appropriate therapeutic potential.
Antibody drug conjugates require target binders that support internalization, whereas antibody effector function requires sustained localization to the cell membrane to accomplish robust activity. Approaches for monoclonal antibodies and bispecific antibodies including immune cell engagers are also welcomed. Antibody characterization will also be addressed, and understanding the range of affinities (<0.1–50 nm), kinetics, domain/bin binding, among other properties, should be explained. How this is completed through in vivo and in vitro antibody discovery will serve as the backbone of this issue.
Dr. Alexander J. Bankovich
Guest Editor
Manuscript Submission Information
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Keywords
- hybridoma
- antibody discovery
- immunizations
- display technologies
- effector function
- monoclonal antibodies
- bispecific antibodies
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