Interference of Bacterial Signaling as a New Strategy for Treatment of AMR Pathogens

Dear Colleagues,

The increase and spread of AMR (antimicrobial resistance) pathogens with a shortage of new antimicrobial agents are critical issues. Therefore, new approaches are needed for the treatment of infections caused by these pathogens. Bacteria use particular signal molecules when they encounter environmental changes or contact with other bacterial members, then alter their gene expression. This manner termed “bacterial signaling” has been observed in many species including animal and plant pathogens. There is increasing evidence that it is closely associated with bacterial virulence, and characterized as virulence determinants to establish infections. Thus, bacterial signaling is proposed as a potential target for the development of antimicrobial agents. In the past two decades, many attempts to interfere with bacterial signaling are have been conducted with great interest. This Special Issue will provide updates on topics related to bacterial signaling interference and conquering refractory AMR infections. We invite manuscripts on studies that include the following topics:

• Chemical compounds, proteins, or nucleic acids targetting bacterial signaling and their molecular mechanisms
• Innovative chemotherapy applications and the use of inhibitors of bacterial signaling (such as combination chemotherapy)

Dr. Hidetada Hirakawa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.