Antimicrobial and Anti-Infective Activity of Natural Products, 3rd Edition
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Plant-Derived Antibiotics".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 148
Special Issue Editors
Interests: antimicrobial activity; bioactive compounds; mechanisms of action; natural products
Special Issues, Collections and Topics in MDPI journals
Interests: antimicrobials; mechanisms of action; host-pathogen interactions
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antimicrobial drugs have transformed the field of medicine since their introduction; however, the growing problem of antimicrobial resistance poses a threat to these advancements, making it essential to develop new therapeutic approaches. In this context, natural products remain an unparalleled reservoir of chemical diversity, offering not only direct antimicrobial activity but also sophisticated anti-infective mechanisms. Building on the success of our first two editions, which collectively published 34 papers, this 3rd Edition expands its scope with increased selectivity to reflect the maturation of the field. While continuing to welcome rigorous foundational research, this edition places renewed priority on studies that achieve mechanistic depth and demonstrate translational potential. We invite submissions on antivirulence agents, resistance-inhibiting compounds (e.g., efflux pumps and β-lactamase inhibitors), antibiotic-producing microorganisms such as Streptomyces spp., and synergistic drug interactions. We strongly encourage the development of robust infection models, including in vivo studies, clinical assays, and in silico investigations, which should be rigorously validated in vitro. Manuscripts limited to crude extract screening or zone-of-inhibition assays will not be considered; acceptable work must demonstrate mechanistic clarity and quantified potency (e.g., MIC, IC50). By demanding higher evidence standards, this edition aims to accelerate the translation of natural compounds and extracts for clinical relevance. We cordially invite you to contribute original research that meets these rigorous criteria and advances the frontiers of anti-infective natural products.
Dr. Valério Monteiro-Neto
Dr. Elizabeth S. Fernandes
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antibiotic-producing microorganisms
- antimicrobial activity
- antimicrobial resistance
- antivirulence therapy
- beta-lactamase inhibition
- clinical evaluation
- drug synergism
- efflux pump inhibitors
- infection models
- mechanism of action
- natural products
- Streptomyces spp.
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