Marine-Derived Antibiotics

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 7

Special Issue Editors


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Guest Editor
Bioorganic Chemistry Laboratory, Department of Physics, University of Trento, Via Sommarive 14, I-38123 Povo-Trento, Italy
Interests: natural products chemistry; marine metabolites; structural characterization; medicinal chemistry; synthesis of biologically active molecules; structure-based drug design; virtual screening
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Bioorganic Chemistry Laboratory, Department of Physics, University of Trento, Via Sommarive 14, I-38123 Povo-Trento, Italy
Interests: medicinal chemistry; structure-based drug design; molecular docking; DFT calculation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Metabolites produced by marine organisms still represent a novel resource of unusual bioactive molecules with therapeutic potential, characterized by the chemical and biological diversity of the immeasurable and partially unknown marine environment. Marine secondary metabolites are selected in Nature to reach optimal activity and perform specialized defense functions, including bacterial inhibition. However, the drawback of their scarce amounts prevents a full biological investigation and applications.

Marine natural products can be sources of relevant new antibiotics. Enhancing their biogenetic production and optimizing the isolation and identification procedures are examples of improving their role in medicinal chemistry and drug development.

Furthermore, organic synthesis allows us to provide suitable amounts of the natural antibacterial hits and to produce analogs with a more favorable drug-likeness. Prediction of the physico-chemical properties and docking calculation are decisive in selecting the most promising structures for providing the Nature-inspired antibiotics.

These are just a few strategies to find solutions to the ever-growing global problem of antibiotic resistance.

The proposed Special Issue aims to provide relevant contributions in the form of original research articles, review articles, and short communications that discuss advances in all aspects of these and other approaches.

Dr. Ines Mancini
Dr. Andrea Defant
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • marine natural products
  • structural characterization
  • improved production of bioactive secondary metabolites
  • organic synthesis
  • structure–activity relationship (SAR)
  • pathogen bacteria inhibition
  • antibiofilm activity
  • computational analysis
  • drug discovery
  • drug delivery systems

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Published Papers

This special issue is now open for submission.
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