Marine-Derived Antibiotics
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".
Deadline for manuscript submissions: 30 June 2026 | Viewed by 48
Special Issue Editors
Interests: natural product chemistry; structural characterization of secondary metabolites; organic synthesis of bioactive molecules; medicinal chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; structure-based drug design; molecular docking; DFT calculation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolites produced by marine organisms still represent a novel resource of unusual bioactive molecules with therapeutic potential, characterized by the chemical and biological diversity of the immeasurable and partially unknown marine environment. Marine secondary metabolites are selected in Nature to reach optimal activity and perform specialized defense functions, including bacterial inhibition. However, the drawback of their scarce amounts prevents a full biological investigation and applications.
Marine natural products can be sources of relevant new antibiotics. Enhancing their biogenetic production and optimizing the isolation and identification procedures are examples of improving their role in medicinal chemistry and drug development.
Furthermore, organic synthesis allows us to provide suitable amounts of the natural antibacterial hits and to produce analogs with a more favorable drug-likeness. Prediction of the physico-chemical properties and docking calculation are decisive in selecting the most promising structures for providing the Nature-inspired antibiotics.
These are just a few strategies to find solutions to the ever-growing global problem of antibiotic resistance.
The proposed Special Issue aims to provide relevant contributions in the form of original research articles, review articles, and short communications that discuss advances in all aspects of these and other approaches.
Prof. Dr. Ines Mancini
Dr. Andrea Defant
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- marine natural products
- structural characterization
- improved production of bioactive secondary metabolites
- organic synthesis
- structure–activity relationship (SAR)
- pathogen bacteria inhibition
- antibiofilm activity
- computational analysis
- drug discovery
- drug delivery systems
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