Special Issue "Uterine Meaning in Diseases of Animals"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editor

Dr. Anna. J. Korzekwa
E-Mail Website
Guest Editor
Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences, Olsztyn, Poland
Interests: corpus luteum; uterus; adenomyosis; cytokines; arachidonic acid metabolites; pregnancy; bovine; cervidae

Special Issue Information

Dear Colleagues,

The origin of reproductive tract diseases in farm and domestic animals is associated with systemic inflammatory processes or inflammations within the reproductive organs. The influence of nutrition on the condition of the organism, including the proper course of female reproductive processes, is very important. Some genetic predisposition also plays a role in uterine diseases. Depending on the species, it is known that a disturbed maternal transmission system and uterine environment may contribute to dysfunction during pregnancy at various stages.

In farm animals, persistent diseases within the reproductive system—including the uterus—cause economic losses in breeding in the long-term balance. On the other hand, the knowledge of molecular factors and signaling pathways induced during uterine endometrium and myometrium dysfunction in selected species may constitute a research model for female diseases.

This Research Topic is gathering original research, reviews, brief research reports, and case reports.

Dr. Anna. J. Korzekwa
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

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Keywords

  • uteum
  • uterus
  • adenomyosis
  • cytokines
  • arachidonic acid metabolites
  • pregnancy

Published Papers (1 paper)

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Research

Article
Expression of Transforming Growth Factor Beta Isoforms in Canine Endometrium with Cystic Endometrial Hyperplasia–Pyometra Complex
Animals 2021, 11(6), 1844; https://doi.org/10.3390/ani11061844 - 21 Jun 2021
Viewed by 564
Abstract
Cystic endometrial hyperplasia (CEH) and pyometra are the most frequently diagnosed uterine diseases affecting bitches of different ages. Transforming growth factor beta (TGF-β) has been classified in females as a potential regulator of many endometrial changes during the estrous cycle or may be [...] Read more.
Cystic endometrial hyperplasia (CEH) and pyometra are the most frequently diagnosed uterine diseases affecting bitches of different ages. Transforming growth factor beta (TGF-β) has been classified in females as a potential regulator of many endometrial changes during the estrous cycle or may be involved in pathological disorders. The aim of this study was to determine the expression of TGF-β1, -β2 and -β3 in the endometrium of bitches suffering from CEH or a CEH–pyometra complex compared to clinically healthy females (control group; CG). A significantly increased level of TGF-β1 mRNA expression was observed in the endometrium with CEH–pyometra compared to CEH and CG. Protein production of TGF-β1 was identified only in the endometrium of bitches with CEH–pyometra. An increase in TGF-β3 mRNA expression was observed in all the studied groups compared to CG. The expression of TGF-β2 mRNA was significantly higher in CEH and lower in CEH–pyometra uteri. The results indicate the presence of TGF-β cytokines in canine endometrial tissues affected by proliferative and degenerative changes. However, among all TGF-β isoforms, TGF-β1 could potentially be a key factor involved in the regulation of the endometrium in bitches with CEH–pyometra complex. Full article
(This article belongs to the Special Issue Uterine Meaning in Diseases of Animals)
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