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Animals
Special Issues
Novel Approaches to Enhancing Poultry Health: From Bench to Farm
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Novel Approaches to Enhancing Poultry Health: From Bench to Farm

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Nutrition".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 812

Special Issue Editors

Dr. Yueping Chen

E-Mail Website
Guest Editor
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
Interests: feed additives; broiler; intestinal health
Special Issues, Collections and Topics in MDPI journals
Dr. Hao Zhang

E-Mail Website
Guest Editor
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China
Interests: antioxidant; plant extracts; oxidative stress; intestinal health; mitochondrial function
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on innovative strategies to enhance poultry health, with a particular emphasis on feed formulation, feed additives, feed processing techniques, and management practices that optimize gut health—a critical factor in disease prevention, nutrient absorption, and overall productivity. As the poultry industry shifts toward sustainable and antibiotic-free production, advancements in functional feeds, probiotics, prebiotics, enzymes, and precision feeding systems play a pivotal role in strengthening intestinal integrity, immunity, and performance. We invite original research and reviews on dietary interventions, feed processing innovations, and farm management protocols that improve microbial balance, reduce pathogens, and enhance nutrient utilization. Contributions may also explore the synergistic effects of additives, gut–microbiome interactions, and cost-effective feeding strategies for disease resilience and growth efficiency. By bridging laboratory breakthroughs with practical farm applications, this Special Issue aims to address key challenges in poultry production, including antibiotic reduction, metabolic disorders, and environmental stressors, while ensuring economic viability. Researchers, nutritionists, and industry experts are encouraged to submit findings that advance science-backed and scalable solutions for sustainable poultry health.

Dr. Yueping Chen
Dr. Hao Zhang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • poultry gut health
  • feed nutrition
  • feed additives
  • feed processing
  • management

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Published Papers (1 paper)

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Research

18 pages, 1026 KB  
Article
Effects of Saccharomyces cerevisiae Hydrolysate on Broiler Performance and Gut Health
by Marcello Comi, Davide Lanzoni, Vera Perricone, Xian-Ren Jiang, Jing Lin and Hai-jun Zhang
Animals 2025, 15(17), 2531; https://doi.org/10.3390/ani15172531 - 28 Aug 2025
Viewed by 517
Abstract
In recent years, scientific interest in functional ingredients capable of replacing the non-therapeutic use of antibiotics in animal feed has intensified, fostering the exploration of novel additives such as Saccharomyces cerevisiae hydrolysate (SCH). This study investigated the effect of dietary SCH supplementation on [...] Read more.
In recent years, scientific interest in functional ingredients capable of replacing the non-therapeutic use of antibiotics in animal feed has intensified, fostering the exploration of novel additives such as Saccharomyces cerevisiae hydrolysate (SCH). This study investigated the effect of dietary SCH supplementation on growth performance, intestinal morphology, local immune response, and cecal microbiota composition in Ross 308 broiler chickens. A total of 300 one-day-old male chicks were randomly assigned to two experimental groups, receiving either a standard diet or a diet supplemented with SCH (500 mg/kg during the starter and grower phases; 250 mg/kg during the finisher phase). SCH supplementation significantly improved growth performance during the finisher phase, with increases in final body weight (p = 0.025), average daily gain (p = 0.049), and average daily feed intake (p = 0.027), without significant changes in feed conversion ratio (p > 0.05). Favourable intestinal morphological modifications were observed, with a significant increase in villus height to crypt depth ratio in both the jejunum and ileum at days 28 (p = 0.035 and 0.002, respectively) and 42 (p < 0.001). The expression of pro-inflammatory cytokine genes was significantly reduced, with lower levels of TNF-α, IL-1β, and IL-6, while tight junction protein genes ZO-1 and Occludin were significantly upregulated (p < 0.05). Microbiota profiling revealed higher alpha diversity and greater abundance of Prevotella. These findings highlight SCH as a promising dietary strategy to improve broiler performance, intestinal function, and sustainability in poultry production systems. Full article
(This article belongs to the Special Issue Novel Approaches to Enhancing Poultry Health: From Bench to Farm)
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