Gut and Bone in Health and Disease

Dear Colleagues,

Bone and cartilage homeostasis fluctuates with age and health and depends on hormonal and nutritional modification in both humans and animals. Connective tissue homeostasis is regulated by many factors, which vary in prenatal and postnatal life and can be affected by several hormones, including glucocorticoids needed for normal physiological prenatal growth. Nutrition and toxicological factors also play a special role in development. The quality of food consumed during postnatal life plays an important role in subsequent development. Throughout history, nutrition has served a therapeutic role in the management of many diseases and a main role in the structural development of mammals. It has long-term effects that might be evident later in life.

This is consistent with the hypothesis of the existence of the gut–bone axis. The gastrointestinal tract is a place where basal mineral elements and nutritional ingredients are absorbed. They are needed for proper development of all systems, ensuring proper growth, including bone development, ensuring proper locomotor activity.

In particular, original manuscripts that address any aspects of gut and bone development are invited for this Topical Collection. We also invite original research papers and reviews that address any aspect of the prenatal programming of different systems in laboratory and livestock animals as well as postnatal growth and development. Topics of special interest are the use of hormones, supplements, nutritional factors, as well as nutrition in general in relation to occurrence of antinutritional or toxic factors; animal health and disease; etc.

Prof. Dr. Ewa Tomaszewska
Dr. Siemowit Muszyński
Collection Editors

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