Special Issue "Advances in Small Animal Gastroenterology"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 30 June 2022.

Special Issue Editors

Prof. Dr. Andrea Boari
E-Mail Website
Guest Editor
Veterinary Teaching Hospital, Faculty of Veterinary Medicine, University of Teramo, Località Piano d'Accio, 64100 Teramo, Italy
Interests: small animal internal medicine; gastroenterology; endocrinology; feline medicine
Special Issues and Collections in MDPI journals
Prof. Dr. Edward J. Hall
E-Mail Website
Guest Editor
Langford Vets, Bristol Veterinary School, Bristol BS40 5DU, UK
Interests: gastrointestinal diseases; dietary sensitivity; microbiome
Prof. Dr. David A. Williams
E-Mail Website
Guest Editor
Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA
Interests: exocrine pancreatic and intestinal diseases; intestinal microflora in health and disease; diagnostic testing

Special Issue Information

Dear Colleagues,

Gastrointestinal disease is a very common presentation of pets in veterinary practice, and our understanding of the unique interaction between host genetics, the mucosal immune system, luminal antigens and the microbiome is rapidly expanding. This special issue will provide authoritative evidence-based, scientific articles integrating clinical research papers, reviews, commentaries and unique case reports from international researchers and specialists embracing all aspects of gastroenterological disease in dogs and cats. It will facilitate the dissemination of the latest research and introduce new ideas and suggest research directions.

Prof. Dr. Andrea Boari
Prof. Edward J. Hall
Prof. David A. Williams
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • veterinary
  • gastroenterology
  • small animals
  • dogs
  • cats
  • stomach
  • intestine
  • pancreas

Published Papers (2 papers)

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Research

Article
Effects of Allogeneic Mesenchymal Stem Cell Transplantation in Dogs with Inflammatory Bowel Disease Treated with and without Corticosteroids
Animals 2021, 11(7), 2061; https://doi.org/10.3390/ani11072061 - 10 Jul 2021
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Abstract
Mesenchymal stem cells have proven to be a promising alternative to conventional steroids to treat canine inflammatory bowel disease (IBD). However, their administration requires a washout period of immunosuppressive drugs that can lead to an exacerbation of the symptoms. Therefore, the feasibility and [...] Read more.
Mesenchymal stem cells have proven to be a promising alternative to conventional steroids to treat canine inflammatory bowel disease (IBD). However, their administration requires a washout period of immunosuppressive drugs that can lead to an exacerbation of the symptoms. Therefore, the feasibility and effects of the combined application of stem cells and prednisone in IBD-dogs without adequate response to corticosteroids was evaluated for the first time in this study over a long- term follow up. Two groups of dogs with IBD, one without treatment and another with prednisone treatment, received a single infusion of stem cells. The clinical indices, albumin and cobalamin were determined prior to the infusion and after one, three, six and 12 months. In both groups, all parameters significantly improved at each time point. In parallel, the steroid dosage was gradually reduced until it was suppressed in all patients a year after the cell therapy. Therefore, cell therapy can significantly and safely improve the disease condition in dogs with IBD receiving or not receiving prednisone. Furthermore, the steroid dosage can be significantly reduced or cancelled after the stem cell infusion. Their beneficial effects are stable over time and are long lasting. Full article
(This article belongs to the Special Issue Advances in Small Animal Gastroenterology)
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Article
Comparison of the Therapeutic Effect of Treatment with Antibiotics or Nutraceuticals on Clinical Activity and the Fecal Microbiome of Dogs with Acute Diarrhea
Animals 2021, 11(6), 1484; https://doi.org/10.3390/ani11061484 - 21 May 2021
Viewed by 791
Abstract
Dogs with acute diarrhea are often presented to clinical practice and, although this generally represents a self-limiting condition, antibiotics are still frequently used as treatment. The aim of this study was to evaluate the effects in dogs with acute non-hemorrhagic diarrhea of the [...] Read more.
Dogs with acute diarrhea are often presented to clinical practice and, although this generally represents a self-limiting condition, antibiotics are still frequently used as treatment. The aim of this study was to evaluate the effects in dogs with acute non-hemorrhagic diarrhea of the administration of an antibiotic combination in comparison to a nutraceutical product. Thirty dogs were enrolled and randomly assigned to two groups: 15 dogs (group A) received a nutraceutical commercial product while 15 dogs (group B) received an antimicrobial combination of metronidazole and spiramycin. For each dog, the Canine Acute Diarrhea Severity Index, the fecal microbiota and the Dysbiosis Index were assessed. Both stool consistency and frequency decreased on day 2 in the dogs of group A compared to baseline, while in group B, these parameters significantly decreased at days 3 and 4. The global concern for rising antibiotic resistance associated with indiscriminate use of antimicrobials, in both humans and animals, suggests the necessity of avoiding empirical and injudicious use of these molecules in diarrheic dogs. These results suggest that the nutraceutical treatment had a similar clinical effect compared to the antibiotic formulation, representing a valid antibiotic-sparing therapeutic approach in canine acute diarrhea. Full article
(This article belongs to the Special Issue Advances in Small Animal Gastroenterology)
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