Molecular Epidemiology of Animal-Associated Fungal and Viral Pathogens

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 726

Special Issue Editor


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Guest Editor
Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA
Interests: veterinary virology; herpes virology; BoHV-1; HSV-1; viral latency; virus–host interaction; viral gene expression; duck hepatitis A viruses; astroviruses; FMDV

Special Issue Information

Dear Colleagues,

Molecular epidemiology is essential to understanding the evolution, transmission, and genetic diversity of animal-associated fungal and viral pathogens. As interactions between animals, humans, and the environment increase, these pathogens pose growing risks to both animal and public health.

This Special Issue highlights the advances in molecular tools and genomic approaches that reveal how these pathogens emerge and spread in domestic, wild, and aquatic animals. We invite original research, reviews, and communications focused on pathogen detection, genetic characterization, phylogenetics, host–pathogen interactions, resistance mechanisms, and molecular diagnostics.

Submissions with relevance to One Health, zoonotic threats, and transboundary disease control are especially encouraged. This issue aims to foster the development of effective surveillance and control strategies through interdisciplinary research at the intersection of animal, human, and environmental health.

Dr. Fouad S. El-Mayet
Guest Editor

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Keywords

  • molecular epidemiology
  • animal pathogens
  • fungal infections
  • viral infections
  • zoonotic diseases
  • genetic characterization
  • phylogenetic analysis
  • evolution

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Published Papers (1 paper)

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Research

22 pages, 2661 KB  
Article
Molecular Diagnostics and Control of Zoonotic Dermatophytosis: First Detection of Trichophyton indotineae in a Dog in Africa
by Hend A. Zineldar, Wafaa M. El-Neshwy, Romeo T. Cristina, Nasser Z. Abouzeid, Mohammed I. Eisa, Florin Muselin, Eugenia Dumitrescu, Adel Abdelkhalek and Yasmine H. Tartor
Animals 2025, 15(17), 2622; https://doi.org/10.3390/ani15172622 - 7 Sep 2025
Viewed by 439
Abstract
Fungal skin infections caused by dermatophytes are of significant veterinary and zoonotic concern. This study investigated the prevalence, risk factors, and treatment outcomes of dermatophytosis in dogs and cats with skin lesions. A total of 140 animals (90 dogs and 50 cats) that [...] Read more.
Fungal skin infections caused by dermatophytes are of significant veterinary and zoonotic concern. This study investigated the prevalence, risk factors, and treatment outcomes of dermatophytosis in dogs and cats with skin lesions. A total of 140 animals (90 dogs and 50 cats) that presented with skin lesions (alopecia, crusts, pruritus, and scales) were examined. Identification of dermatophyte isolates relied on both phenotypic characteristics and molecular techniques. The molecular approach involved PCR and sequencing of ribosomal DNA regions (ITS1, ITS2, and 5.8S rDNA), complemented by Restriction Fragment Length Polymorphism (RFLP). Treatment regimens included topical clotrimazole, systemic itraconazole, supportive therapy, and a dermatophyte vaccine. Of the 90 dog samples examined, 47 (52.22%) were positive for fungal culture (p = 0.65). In cats, 35 samples (70%) were positive (p < 0.0001). Microsporum canis was the most significant (p < 0.0001) prevalent isolate (60%), followed by Trichophyton mentagrophytes (20%). This study reported the first isolation of T. indotineae in Egypt. Younger animals (<1 year) exhibited a significantly (p < 0.05) higher risk of infection compared with adults (>1 year). Indoor/outdoor housing in cats significantly reduced the risk of infection when compared with indoor housing (p < 0.0001; odds ratio = 0.05). Combination therapy using itraconazole, clotrimazole, supportive treatment, and a dermatophyte vaccine resulted in the fastest clinical recovery (p < 0.0001). These findings underscore the importance of accurate diagnosis and effective treatment strategies for managing dermatophytosis in pets and preventing zoonotic transmission. Full article
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