Recent Advances in Mammary Tumors in Companion Animals

Dear Colleagues,

Mammary tumors are among the most frequently diagnosed neoplastic diseases in companion animals and continue to pose significant clinical and diagnostic challenges. Over recent decades, key advances in veterinary oncology have improved our understanding of the biological behavior of these tumors, refined diagnostic methodologies, and expanded the range of available prognostic and predictive tools. Progress in molecular pathology, immunohistochemistry, and tumor microenvironment analysis has enhanced our ability to characterize tumor subtypes, evaluate patterns of invasion, and better estimate clinical outcomes.

At the same time, new technologies such as digital pathology, advanced imaging, and high-throughput analytical platforms are contributing to greater diagnostic accuracy and promoting more standardized criteria for histopathological evaluation. These developments support more precise decision-making and help guide the selection of appropriate therapeutic approaches.

This Special Issue will showcase recent scientific contributions that reflect the current state of knowledge on mammary tumors in companion animals. We invite original studies and comprehensive reviews addressing pathology, diagnosis, treatment, molecular features, classification updates, and emerging technologies. By integrating diverse perspectives from researchers and clinicians, this Special Issue will advance our understanding of mammary neoplasia and inspire further innovation in veterinary oncology. 

We look forward to receiving your contributions.

Dr. Geovanni Dantas Cassali
Prof. Valentina Zappulli
Dr. Carlos Eduardo Fonseca-Alves
Dr. Giovanni Pietro Burrai
Guest Editors

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