Special Issue "Atherosclerosis: Molecular Mechanisms and Therapeutic Advances"
A special issue of J (ISSN 2571-8800).
Deadline for manuscript submissions: closed (15 October 2018) | Viewed by 7797
Special Issue Editors

Interests: aging; oxidative stress; nitric oxide; endothelial cells; endothelial progenitor cells; angiogenesis; inflammation; cell senescence; apoptosis; atherosclerosis; diabetes, endothelial dysfunction, sirtuins and cardiovascular disease; natural products; betaines; health; bioactive compounds; free radicals; antioxidants; ergothioneine; cell cycle; cancer-related biochemical pathways; cell proliferation; senescence; cancer cell death; epigenetic regulation; sirtuins and cancer
Special Issues, Collections and Topics in MDPI journals

Interests: oxidative stress; endothelial cells; endothelial progenitor cells; endothelial dysfunction; inflammation; cell senescence; atherosclerosis; diabetes; sirtuins and cardiovascular disease; natural products; betaines; bioactive compounds; free radicals; antioxidants; ergothioneine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development of atherosclerosis, a complex multifactorial process, is, at least in part, controlled by the functional state of the vascular endothelium, influenced by a broad set of cardiovascular risk factors. Hypercholesterolemia, hypertension, and diabetes mellitus enhance reactive oxygen species generation, resulting in oxidative modification of lipoproteins and phospholipids, all mechanisms that contribute to atherogenesis. A pivotal role for inflammation in the pathogenesis of atherosclerosis has been recognized and proved at molecular levels. However, despite current knowledge, results coming from genome wide association studies are expected to uncover the complex inflammatory process subtending atherosclerosis, thus opening a new scenario for tailored target therapy. Moreover, several pieces of evidence point towards the crosstalk between long non-coding RNAs and vasculature in regulating the development of vessel lining and recruitment of immune cells, such as macrophages, at the site of injury and inflammation. In particular, the modulation of atherosclerosis by long non-coding RNAs has brought significant attention over the past few years. This Special Issue welcomes both original papers and review articles addressing one or several of the above-mentioned issues, or of the topics mentioned in the keywords listed below.
Prof. Dr. Maria Luisa Balestrieri
Dr. Nunzia D'Onofrio
Guest Editors
Manuscript Submission Information
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Keywords
- Endothelial dysfunction
- Arterial Disease
- Atherosclerosis
- Atherosclerotic plaque
- Vascular diseases
- Inflammation
- Reactive oxygen species
- Oxidative stress
- Nitric oxide
- Long non-coding RNAs
- Whole-genome sequencing
- Genetics, Anti-inflammatory drugs
- Genome wide association study
- DNA sequencing