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Cancers | Issue Cover Articles Published in 2025

30 December 2025

The articles below have been selected as 2025 issue cover articles by the Editorial Office of Cancers (ISSN: 2072-6694). These articles came from multiple fields within the scope of Cancers, and we hope they can provide insights and references for scholars in related fields.
  1. “Components of the Endosome-Lysosome Vesicular Machinery as Drivers of the Metastatic Cascade in Prostate Cancer”
    by Bukuru Dieu-Donne Nturubika, Jessica Logan, Ian R. D. Johnson, Courtney Moore, Ka Lok Li, Jingying Tang, Giang Lam, Emma Parkinson-Lawrence, Desmond B. Williams, James Chakiris et al.
    Cancers 2025, 17(1), 43; https://doi.org/10.3390/cancers17010043

  1. “Venous Thromboembolism in Patients with Neuroendocrine Neoplasms: A Systematic Review of Incidence, Types, and Clinical Outcomes”
    by Sara Massironi, Lorenzo Gervaso, Fabrizio Fanizzi, Paoletta Preatoni, Giuseppe Dell’Anna, Nicola Fazio and Silvio Danese
    Cancers 2025, 17(2), 212; https://doi.org/10.3390/cancers17020212

  1. “An Assessment of Young Adults’ Awareness and Knowledge Related to the Human Papillomavirus (HPV), Oropharyngeal Cancer, and the HPV Vaccine”
    by Eric N. Davis and Philip C. Doyle
    Cancers 2025, 17(3), 344; https://doi.org/10.3390/cancers17030344

  1. “Therapeutic Targeting of the Janus Kinase/Signal Transducer and Activator of Transcription Pathway in Cutaneous T-Cell Lymphoma”
    by Alisha Kashyap, Julia Dai and Xiao Ni
    Cancers 2025, 17(4), 568; https://doi.org/10.3390/cancers17040568

  1. “AI Model for Predicting Anti-PD1 Response in Melanoma Using Multi-Omics Biomarkers”
    by Axel Gschwind and Stephan Ossowski
    Cancers 2025, 17(5), 714; https://doi.org/10.3390/cancers17050714

  1. “Immunological Network Signature of Naïve Non-Oncogene-Addicted Non-Small Cell Lung Cancer Patients Treated with Anti-PD1 Therapy: A Pilot Study”
    by Pasquale Sibilio, Ilaria Grazia Zizzari, Alain Gelibter, Marco Siringo, Lucrezia Tuosto, Angelica Pace, Angela Asquino, Flavio Valentino, Arianna Sabatini, Manuela Petti et al.
    Cancers 2025, 17(6), 922; https://doi.org/10.3390/cancers17060922

  1. “From Diagnosis to Survivorship: The Role of Social Determinants in Cancer Care”
    by Abiha Abdullah, Zeyu Liu and Michele Molinari
    Cancers 2025, 17(7), 1067; https://doi.org/10.3390/cancers17071067

  1. “Detection of ESR1 Mutations in Tissue and Liquid Biopsy with Novel Next-Generation Sequencing and Digital Droplet PCR Assays: Insights from Multi-Center Real Life Data of Almost 6000 Patients”
    by Srushti Borkar, Fenja Markus, Agnes Oetting, Stefanie Schmidt, Christine Vössing, David Horst, Markus Möbs, Elena I. Braicu, Frank Griesinger, Katja Horling et al.
    Cancers 2025, 17(8), 1266; https://doi.org/10.3390/cancers17081266

  1. “Understanding the Impact of Deep Learning Model Parameters on Breast Cancer Histopathological Classification Using ANOVA”
    by Nerea Hernandez, Francisco Carrillo-Perez, Francisco M. Ortuño, Ignacio Rojas and Olga Valenzuela
    Cancers 2025, 17(9), 1425; https://doi.org/10.3390/cancers17091425

  1. “Long Non-Coding RNAs and RNA-Binding Proteins in Pancreatic Cancer Development and Progression”
    by Pit Preckwinkel, Khursheed Ul Islam Mir, Florian W. Otto, Hend Elrewany, Andrea Sinz, Stefan Hüttelmaier, Nadine Bley and Tony Gutschner
    Cancers 2025, 17(10), 1601; https://doi.org/10.3390/cancers17101601

  1. “Protein Biomarkers Enable Sensitive and Specific Cervical Intraepithelial Neoplasia (CIN) II/III+ Detection: One Step Closer to Universal Cervical Cancer Screening”
    by Samrin F. Habbani, Sayeh Dowlatshahi, Nathanael Lichti, Meaghan Broman, Lucy Tecle, Scott Bolton, Lisa Flowers, Rafael Guerrero-Preston, Jacqueline C. Linnes and Sulma I. Mohammed
    Cancers 2025, 17(11), 1763; https://doi.org/10.3390/cancers17111763

  1. “New Approaches in Radiotherapy”
    by Matthew Webster, Alexander Podgorsak, Fiona Li, Yuwei Zhou, Hyunuk Jung, Jihyung Yoon, Olga Dona Lemus and Dandan Zheng
    Cancers 2025, 17(12), 1980; https://doi.org/10.3390/cancers17121980

  1. “Role of Vascular Liver Diseases in Hepatocellular Carcinoma Development”
    by Lucia Giuli, Valeria De Gaetano, Giulia Venturini, Ersilia Arvonio, Marco Murgiano, Antonio Gasbarrini, Francesco Santopaolo and Francesca Romana Ponziani
    Cancers 2025, 17(13), 2060; https://doi.org/10.3390/cancers17132060

  1. “Chronic Lymphocytic Leukemia: Novel Therapeutic Targets Under Investigation”
    by Madhavi Nayyar, Ricardo C. B. de Menezes, Sikander Ailawadhi and Ricardo D. Parrondo
    Cancers 2025, 17(14), 2298; https://doi.org/10.3390/cancers17142298

  1. “Supercharged Natural Killer (sNK) Cells Inhibit Melanoma Tumor Progression and Restore Endogenous NK Cell Function in Humanized BLT Mice”
    by Kawaljit Kaur, Paytsar Topchyan and Anahid Jewett
    Cancers 2025, 17(15), 2430; https://doi.org/10.3390/cancers17152430

  1. “Risk Stratification of Thyroid Nodules Using Ultrasound Cine-Loop Video Sequences”
    by Tabea Nikola Schmidt, Martin Freesmeyer, Christian Kühnel, Falk Gühne, Larissa Rosenbaum, Robert Drescher and Philipp Seifert
    Cancers 2025, 17(16), 2616; https://doi.org/10.3390/cancers17162616

  1. “Workflow Efficiency in Vaginal Cuff High Dose Rate Brachytherapy Using Artificial Intelligence-Based Organ Segmentation and Multi-Channel Cylinder Modeling”
    by Yohan A. Walter, Lane Rosen, Olivia Moncrief, Bethany Broekhoven, Troy Jacobs, Joseph Syh, Joseph Dugas, Kelsi Hoffnung, Mitchell Wolden, Heidi Wimberly et al.
    Cancers 2025, 17(17), 2751; https://doi.org/10.3390/cancers17172751

  1. “Revealing the Angiogenic Signature of FH-Deficient Breast Cancer: Genomic Profiling and Clinical Implications”
    by Liat Anabel Sinberger, Noa Keren-Khadmy, Assaf Goldberg, Tamar Peretz-Yablonski, Amir Sonnenblick and Mali Salmon-Divon
    Cancers 2025, 17(18), 2942; https://doi.org/10.3390/cancers17182942

  1. “Spatial Transcriptomics Reveals Distinct Architectures but Shared Vulnerabilities in Primary and Metastatic Liver Tumors”
    by Swamy R. Adapa, Sahanama Porshe, Divya Priyanka Talada, Timothy M. Nywening, Mattew L. Anderson, Timothy I. Shaw and Rays H. Y. Jiang
    Cancers 2025, 17(19), 3210; https://doi.org/10.3390/cancers17193210

  1. “The Urokinase-Type Plasminogen Activator Receptor (uPAR) as a Mediator of Physiological and Pathological Processes: Potential Therapeutic Strategies”
    by Ali Iftikhar, Niaz Mahmood and Shafaat A. Rabbani
    Cancers 2025, 17(20), 3309; https://doi.org/10.3390/cancers17203309

  1. “Challenges in the Evolving Role of Calreticulin as a Promising Target for Precision Medicine in Myeloproliferative Neoplasms”
    by Alessandro Costa and Massimo Breccia
    Cancers 2025, 17(21), 3397; https://doi.org/10.3390/cancers17213397

  1. “Real-World Comparative Study of Atezolizumab-Based Chemotherapy Regimens in Advanced Non-Small Cell Lung Cancer”
    by Ayaka Ohiwa, Tadashi Nishimura, Tadashi Sakaguchi, Hajime Fujimoto, Shuji Kodama, Atsushi Fujiwara, Hiroki Nakahara, Taichi Isobe, Takaya Hirai, Akihiko Yagi et al.
    Cancers 2025, 17(22), 3630; https://doi.org/10.3390/cancers17223630

  1. “SBFI Inhibitors Reprogram Transcriptomic Landscape of Prostate Cancer Cells Leading to Cell Death”
    by Shubhra Rajput, Joseph F. LaComb, Chris Gordon, Hehe Wang, Manisha Sarder, Martin Kaczocha, Iwao Ojima and Agnieszka B. Bialkowska
    Cancers 2025, 17(23), 3723; https://doi.org/10.3390/cancers17233723

  1. “The Rise of Fine-Tuned CAR-Based Therapies Against Acute Myeloid Leukemia”
    by Alejandro Segura Tudela, Ron Geller, Bruno Paiva, Sara Carmen Torres Sánchez, Elisa González Romero, Pilar Lloret Madrid, Pedro Chorão, Javier de la Rubia, Pau Montesinos and Manuel Guerreiro
    Cancers 2025, 17(24), 3892; https://doi.org/10.3390/cancers17243892
Prof. Dr. Eiichiro Fukusaki Appointed Section Editor-in-Chief of Section “Food Metabolomics” in Metabolites
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