Beyond Swelling: A Review of Postoperative Lymphedema in Aesthetic Surgery
Abstract
1. Introduction
2. Lymphedema Incidence in Aesthetic Surgery
2.1. Body Contouring Procedures
2.2. Facial Procedures
Procedure | Reported Findings/Outcomes | Risk Factors/Notes |
---|---|---|
Body Contouring | ||
Liposuction | 1.7% persistent edema > 6 weeks [8] | Resolved conservatively in most cases |
Brachioplasty | - 6.9% combined seroma/lymphocele [9] - 1.5% distal edema resolving with compression [10] - 1.3% (brachioplasty alone) vs. 3.2% (brachioplasty + liposuction) with persistent edema/lymphedema [11] | Lymph-sparing lipobrachiopexy preserved physiological lymphatic drainage on ICG lymphography at 1 year [13] |
Thighplasty | 8.2% postoperative lymphedema (resolved < 2 months) [12] | - Risk increased with vertical thigh lift, hypothyroidism, and male sex - Higher BMI showed a negative association |
Abdominoplasty | 85% with altered drainage on lymphoscintigraphy: 65% rerouted to axillary nodes, 10% dual drainage, 10% indeterminate [14]. | Stable rerouting persisted at 1–6 months, indicating durable long-term change [14] |
Facial Procedures | ||
Blepharoplasty | Increased lymphatic vessel density correlated with faster edema resolution and scar maturation [16] | Older patients had lower density leading to delayed recovery |
Facelift | Edema is predictable: peaks at POD 7 (+2.8%, p = 0.0025), mostly resolved by 1 month [18] | Wide flaps, platysma plication, medial procedures, tight compression led to increased edema [17] |
Multiple Surgeries | Case reports: ACL after breast reduction in women with prior abdominoplasty/cesarean (47-yr-old, 74-yr-old) [15] | Suggests cumulative trauma predisposes to delayed complications |
3. Imaging for Early Lymphatic Compromise
- Lymphoscintigraphy: This is a functional imaging gold standard for lymphatics. It involves injecting a small amount of radioactive tracer into an area and using a camera to track its uptake and transport through lymphatic vessels and nodes. Bassalobre et al. employed lymphoscintigraphy to map abdominal drainage before and after abdominoplasty [14]. The study highlights lymphoscintigraphy as an effective, noninvasive method for visualizing and tracking changes in superficial lymphatic drainage patterns following abdominoplasty. Specifically, intradermal injections of technetium-99m-labeled dextran (dextran 500–99mTc) allowed for dynamic and static imaging of lymphatic flow from standardized points on the infraumbilical abdomen. Using a gamma camera, the research team was able to map lymphatic drainage at three key time points—preoperatively and at 1 and 6 months postoperatively. Using this technique, the study revealed that while all patients had inguinal drainage preoperatively, 65% rerouted to axillary nodes after surgery, with only 15% maintaining their original drainage. These changes remained consistent between 1 and 6 months, demonstrating lymphoscintigraphy’s utility in capturing long-term lymphatic remodeling [14].
- Indocyanine Green (ICG) Lymphography: ICG lymphography is a dynamic, high-resolution imaging technique that involves intradermal injection of ICG dye, which binds to plasma proteins and is taken up by lymphatic vessels. Using near-infrared light, the dye fluoresces, allowing real-time visualization of lymphatic flow and structure. In the study by Bianchi et al., ICG lymphography was used to assess lymphatic function in patients undergoing lipobrachiopexy [13]. Patients received intradermal ICG injections, and lymphatic flow was imaged preoperatively and at 1, 6, and 12 months postoperatively. The authors found that lymphatic drainage patterns remained physiologic in all cases, with preserved linear tracer progression and no clinical evidence of lymphedema at one-year follow-up. ICG lymphography also detected minor tracer extravasation in two patients at one month, which resolved by one year, underscoring the sensitivity of this technique in identifying early, subclinical lymphatic disruption [13].
4. Management Strategies and Interventions
- Conservative management: The mainstay for treating edema or mild lymphedema is Complete Decongestive Therapy (CDT), which consists of manual lymphatic drainage, compression therapy, exercise, and skin care. In the aesthetic surgery setting, surgeons implement many of these principles as part of standard postoperative care. Postoperative compression garments are commonly used in aesthetic and reconstructive procedures, including abdominoplasty, breast surgery, and facelifts. Current evidence primarily supports their benefit in reducing edema and ecchymosis after rhinoplasty and in decreasing postoperative pain following breast and abdominal surgery [19]. For example, liposuction patients wear graded compression garments on treated areas for weeks. Compression helps prevent fluid re-accumulation and encourages lymphatic and venous return [8].
- Manual Lymphatic Drainage (MLD): Manual lymphatic drainage (MLD) is a cornerstone of nonsurgical lymphedema management and is gaining prominence as a supportive therapy in plastic and reconstructive surgery. MLD is a specialized massage technique that employs slow, rhythmic hand movements to stimulate lymphatic flow and reroute lymph through functioning channels, particularly after surgical disruption. It is a key component of CDT, used alongside compression, exercise, and skin care [20]. The physiological mechanisms of MLD are still under investigation, but several theories suggest that MLD enhances lymphatic drainage by increasing intrinsic vessel contractility, reducing distal lymphatic pressure, and improving interstitial reabsorption through elevated interstitial pressure [20]. In aesthetic surgery, MLD has been increasingly applied in the postoperative setting to manage swelling, promote healing, and optimize aesthetic outcomes. Marxen et al. [20] emphasizes its utility following high-risk procedures such as liposuction, abdominoplasty, and brachioplasty, where lymphatic disruption is common. For example, abdominoplasty can shift drainage from the inguinal to axillary nodes, creating a mismatch in flow that may contribute to seroma or edema. MLD may help address this mismatch, particularly during the critical 3–6 month recovery window when edema and fibrosis are most pronounced [20].
Section | Approach/Modality | Summary | Representative Findings/Application |
---|---|---|---|
Imaging for Early Lymphatic Compromise | Lymphoscintigraphy | Functional nuclear medicine study using intradermal 99mTc-dextran; maps superficial drainage pathways | Bassalobre et al.: after abdominoplasty, 65% rerouted to axillary nodes, 15% retained inguinal drainage, 10% dual drainage, 10% indeterminate; patterns stable from 1–6 months [14]. |
Indocyanine Green (ICG) lymphography | Near-infrared fluorescence technique after intradermal ICG injection; dynamic, high-resolution visualization of superficial lymphatic flow | Bianchi et al.: after lipobrachiopexy, physiologic linear drainage preserved at 1 year; minor tracer extravasation in 2 pts at 1 month resolved spontaneously [13]. | |
Management Strategies: Complete Decongestive Therapy | Compression therapy | Use of graded garments to limit fluid re-accumulation and encourage venous/lymphatic return | Ormseth et al.: Broadly used after aesthetic procedures; strongest evidence for reducing edema/ecchymosis after rhinoplasty and postoperative pain after breast and abdominal surgery [19] |
Manual Lymphatic Drainage (MLD) | Gentle, rhythmic massage to enhance lymphatic flow and reroute fluid through intact channels | Marxen et al.: highlighted utility after abdominoplasty, brachioplasty, and liposuction, where lymphatic disruption is common [20]. |
5. Discussion
6. Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
ACL | Acquired Cutaneous Lymphangiectasia |
ICG | Indocyanine Green |
VCA | Vascularized composite allotransplants |
POD | Postoperative Day |
CDT | Complete Decongestive Therapy |
MLD | Manual lymphatic drainage |
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Phondge, V.; Dornbrand-Lo, M.; Deshpande, P.; Wong, A.K. Beyond Swelling: A Review of Postoperative Lymphedema in Aesthetic Surgery. Lymphatics 2025, 3, 26. https://doi.org/10.3390/lymphatics3030026
Phondge V, Dornbrand-Lo M, Deshpande P, Wong AK. Beyond Swelling: A Review of Postoperative Lymphedema in Aesthetic Surgery. Lymphatics. 2025; 3(3):26. https://doi.org/10.3390/lymphatics3030026
Chicago/Turabian StylePhondge, Varoon, Maya Dornbrand-Lo, Pooja Deshpande, and Alex K. Wong. 2025. "Beyond Swelling: A Review of Postoperative Lymphedema in Aesthetic Surgery" Lymphatics 3, no. 3: 26. https://doi.org/10.3390/lymphatics3030026
APA StylePhondge, V., Dornbrand-Lo, M., Deshpande, P., & Wong, A. K. (2025). Beyond Swelling: A Review of Postoperative Lymphedema in Aesthetic Surgery. Lymphatics, 3(3), 26. https://doi.org/10.3390/lymphatics3030026